Dubininkienė, Milda

There are no diagnostic tests or consent international definition for long COVID in children [1]. Long-COVID is a typical condition of adults with a history of probable or confirmed SARS-CoV-2 infection in the previous 3 months and with symptoms lasting over 2 months not explained by an alternative diagnosis [2]. We present a case report of a 16 year old girl, who experienced mental health decline after SARSCoV-2 infection that manifested with depressive symptoms. Patient’s mental and somatic condition was evaluated 5 times in one year period and once again after 2 years. Patient attended psychotherapy and was treated with Fluoxetine up to 20 mg a day for reduction of depresive and anxiety symptoms. A reduction of symptoms was registered 2 weeks after begining of treatment but 55 weeks after virus exposition symptoms reoccurred. Certain symptoms, such as anxiety, difficulties concentrating, and fatigue, persisted despite the reduction of other symptoms. This case report shows dynamics of long-COVID syndrome in 2 year period.

Backgrounds: Children who have contracted COVID are at risk of experiencing a variety of long-lasting symptoms collectively known as prolonged COVID syndrome. According to world data, about 30% of children infected with SARS-CoV-2 will experience certain symptoms. In this study, we aimed to create a continuous follow-up program for children after COVID infection. Moreover, our aim was to improve longterm periodic communication with the patient's parents to discuss her/his condition and timely recognize the signs of prolonged COVID. In addition, provide individualized assistance, monitoring of the patient and symptoms, assessment of the persistence of symptoms, and provide specific treatment. Methods: Continuous follow-up program in the frame of a prospective observational study was created and is conducted in our hospital. The program started in March 2022. Criteria for the inclusion: 1 month up to 18 years of age, diagnosed with COVID-19, or have been diagnosed with MIS-C syndrome according to the clinical criteria. After the inclusion, in a period of one year, 5 medical assessments of the state of health are planned to be carried out. In case of specific symptoms, a patient is referred to a specialist. Results: Currently, ~40 children with their caregivers are included into the program. The median age for inclusion – 9y, 42%-female. Nine children required additional consultation with a pediatric neurologist with the most frequent complaint of headaches. 4 children have ongoing consultations with a psychiatrist and continuous visits are planned. Six children were referred to a pediatric rheumatologist complaining of prolonged joint aches and the assessment regarding autoimmune diseases is ongoing. Conclusions/Learning Points: Our further plans are to collect more data and analyze the symptoms and signs according to age and gender.

Tyrimo tikslas. Ištirti alkoholio vartojimo ryšį su sociodemografiniais, su liga susi-jusiais veiksniais ir gyvenimo kokybe sergant šizofrenija. Metodai. Tyrimas atliktas Lietuvos sveikatos mokslų universiteto ligoninės Kauno klinikų (toliau - Kauno klinikų) Psichiatrijos klinikoje. Naudojantis sociodemografiniu klausimynu, CAGE probleminio alkoholio vartojimo klausimynu ir SF-36 gyvenimo kokybės klausimynu buvo ištirti 47 šizofrenija sergantys asmenys. Rezultatai. Tarp gautų duomenų buvo ištirtas ryšys, naudojantis SPSS programine įranga. Atlikus tyrimą, paaiškėjo, kad probleminis alkoholio vartojimas nustatytas kas trečiam vidutinio amžiaus šizofrenija sergančiam pacientui. Taip pat nustatyta, kad šizofrenija sergančios moterys reikšmingai mažiau yra linkusios į probleminį alkoholio vartojimą nei vyrai. Išvados. Problemiškai alkoholį vartojantys pacientai turi reikšmingai prastesnę socialinę funkciją nei pacientai, kurių alkoholio vartojimas nėra probleminis. Probleminis alkoholio vartojimas nesusijęs nei su šizofrenijos trukme, nei su tuo, kiek kartų ligos metu pacientai gydyti stacionare.