| Creator | Affiliation |
|---|---|
Urbutė, Paulina | |
Data of anamnesis, clinical symptoms, and outcome of the disease.
| URI | Title |
|---|---|
https://doi.org/10.5281/zenodo.8403166 | Zenodo |
https://doi.org/10.3390/v15112265 | Viruses : The Prevalence, Seroprevalence, and Risk Factors of Tick-Borne Encephalitis Virus in Dogs in Lithuania, a Highly Endemic State |
https://hdl.handle.net/20.500.12512/240994 |
| Name | ID |
|---|---|
Research Council of Lithuania | No S-MIP-23-80 |
Lithuanian University of Health Sciences Foundation | No V-789; No V-786; No 2021-V-0671; No 2022-V-0352 |
The Prevalence, Seroprevalence, and Risk Factors of Tick-Borne Encephalitis Virus in Dogs in Lithuania, a Highly Endemic StateItem type:Publication, research article[2023][S1][A002][12]; ; ; ; Viruses, 2023-11-17, vol. 15, no. 11, p. 1-12The rising awareness and increasing number of case reports of tick-borne encephalitis (TBE) in dogs indicate that the virus might be an important tick-borne pathogen in dogs, especially in endemic areas. Therefore, the aim of the present study was to investigate the prevalence rate of TBEV RNA and TBEV-specific antibodies in clinical samples of dogs living in a highly endemic region of Lithuania and to evaluate the main risk factors for severe disease course and death. The blood samples (n = 473) of dogs were collected in two veterinary clinics in central Lithuania. Tick-borne encephalitis virus (TBEV) RNA was detected in 18.6% (88/473; CI 95% 15.2-22.4) and TBEV-specific antibodies were found in 21.6% (102/473; CI 95% 17.9-25.6) of dog blood serum samples after confirmation with a virus neutralization test. The death/euthanasia rate was 18.2% (16/88; CI 95% 10.8-27.8) in PCR-positive dogs. Male dogs were more likely to develop neurological symptoms (p = 0.008). Older dogs (p = 0.003), dogs with the presence of neurological symptoms (p = 0.003), and dogs with the presence of TBEV-specific antibodies (p = 0.024) were more likely to experience worse outcomes of the disease. The results of the present study demonstrate that TBEV is a common and clinically important pathogen in dogs in such endemic countries as Lithuania.
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