Radiological and clinical interfaces of adrenal tumors

Abstract

Aim: To evaluate the clinical, laboratory and radiological data of patients diagnosed with adrenal tumors. Methods: Analysis of medical histories of patients diagnosed with adrenal tumor in 2017-2018. 40 males and females with a mean age of 59.48 ± 12.45 and 63.83 ± 14.92, respectively. Results: 35% of the patients were overweight, and 41.3% - obese. Arterial blood pressure was elevated in 66 (82%) patients. The average heart rate in female patients was 77.48 ± 11.43 bpm, while in male – 78.53 ± 13 bpm. The most common: 1) complaint was high blood pressure (63,8%); 2) comorbidity - arterial hypertension (42,5%); 3) adrenal tumor - adenoma (42,5%); 4) tumor size - 3 cm (25%); and the least common adrenal tumor was aldosteronoma (3,8%). 37 tumors were enhanced according to the CT with a contrast enhancement. Males (30%) were more often diagnosed with bilateral tumors than females (5%). Finally, percental increase of metanephrine and noretanephrine was significantly higher in pheochromocytoma than in other tumors. Conclusions: 1) Differences between gender in BMI, blood pressure and heart rate were not significant. No significant differences were found between male and female complaint analysis. 2) The most common adrenal tumors were adenomas, and the changes in the hormone concentration of adenomas were not statistically significant. Pheochromocytomas were significantly larger than adenomas. Pheochromocytomas enhance statistically significantly more compared to other adrenal tumors. 3) In case of pheochromocytoma, the percentage of increase of metanephrine and normetanephrine is significantly higher than in other tumors.