Selection of the optimal extraction conditions of the polyphenolics from Lavandula angustifolia herbal raw materials

Abstract

Introduction. Today, in the structure of general pathology, lesions of the central nervous system are quite common, which, in addition to the impact of the coronavirus infection since 2019. In Ukraine are additionally caused by the harsh consequences of the military aggression of the Russian Federation. Certain neurological symptoms, organic and symptomatic mental disorders can persist for a long time. To correct the above-mentioned symptoms, therapy with powerful sedatives is used, but for a more "soft" intervention, it is possible to use herbal remedies. Due to its chemical composition Lavandula angustifolia Mill. has a very wide range of pharmacological effects (antibacterial, antimicrobial, sedative, antispasmodic, anti-inflammatory and analgesic) and is actively used in medicine. The raw material is used as a mild sedative for nervous exhaustion and sleep disorders (López et al., 2017). It is part of soothing teas. Lavender tincture is believed to relieve depression, headaches, and anxiety (Malcolm et al., 2018). Special attention is drawn to the antioxidant activity of lavender, which it owes, in particular, to the phenolic compounds in its composition (Dobros et al., 2022). The pharmaceutical industry actively uses lavender to create various medicines and phytoremedies from extracts and essential oils with different modes of action. The aim of the current research is to select optimal conditions for extracting of the total phenolic compounds from different lavender raw materials. [...].