Radiological and clinical features of 150 patients with adrenal tumors in one university center

Abstract

Objective: To analyse the radiological and clinical features of patients with adrenal tumors in one university center, and to tr y to find any regularities, related to clinical data. Methods: Medical documentation of 53 women and 97 men, who had adrenal tumors diagnosed by CT or/and by MRI, were analysed. Essential clinical and laboratory data were documented. Age, height, weight, B MI, systolic and diastolic blood pressure, pulse were recorded together with results of investigation of DHEAS, testosterone, TTH, aldosterone, ACTH, fT4, cortisol, renin, metanefrine, normethanefrine, aldosterone/renin ratio. Results: Age of women and men at the time of AT diagnosis was the same. Concentration of aldosterone, ACTH, cortisol, renin, methanephrine and normethanephrine and aldosterone/renin ratio were investigated with the same frequency in both sexes. TTH, fT4 and DHEAS were assessed more fr equently in female, than in male patients (48, 41 and 50% and 32, 28 and 40% respectively). Surprisingly, testosterone was assessed rarely both in women and men. Without hormone investigations remained 5,5 % of women and 20,6% of men. Unilateral, as well a s bilateral, adrenal tumours were detected with the same frequency in both sexes. Surgery was performed in 7,4% of female, and in 5,2% of male patients. Conclusions: TTH, fT4 and DHEAS were assessed more frequently in female patients. Surprisingly, testos terone was assessed rarely in both sexes. Unilateral, as well as bilateral, adrenal tumours were detected with the same frequency (female vs male patients). In case of bilateral AT, unilateral resection was performed more frequently in female patients.