Validation of Lithuanian Version of Ocular Surface Disease Index Questionnaire

Abstract

Introduction: Administration of questionnaires regarding health-related quality of life evaluation is a crucial step of the diagnostic process. Ocular Surface Disease Index (OSDI) is a worldwide accepted questionnaire for patients experiencing dry eye symptoms. Aim of the study: The purpose of this study is to complete the validation of Lithuanian Version of OSDI and make it available in Lithuanian ophthalmologists’ daily work and research while encountering dry eye disease (DED) patients. Methods: The translation process of original OSDI to Lithuanian language was made by the Mapi Research Trust according to the accepted rules for questionnaire validation. All included DED patients completed the Lithuanian Version of OSDI. Inclusion criteria: native Lithuanian speakers of 18 years or older, who had previously diagnosed DED and gave consent to participate in the study. Patients with ocular infection or vision less than 6/60 in Snellen chart were excluded. Randomly selected subjects were requested to refill the translated OSDI one month later for test-retest reliability evaluation. All participants underwent a comprehensive ophthalmological and specific examination for ocular dryness with non-anesthetic Schirmmer’s test, tear break up time (TBUT) test, fluorescein staining of the cornea. In a randomized manner, a part of subjects was selected to complete Visual Function Questionnaire (VFQ-25) which was compared to Lithuanian Version of OSDI. Results: The study included 90 DED patients of which 75 (83.3%) were female and 15 (16.7%) were male. The age mean (SD) was 65,87 (±17). The Cronbach’s alpha coefficient for the questionnaire was 0.87 and for the three subscales it was 0.78, 0.69 and 0.71, respectively. The translated OSDI and its’ subscales showed good internal consistency. A significant correlation was found for test-retest reliability (n=35). Correlations between Lithuanian Version of OSDI and V[...].