Intrabony defect treatment using autologous platelet-rich fibrin – a case report

Abstract

Objectives: The objective of this case report is to compare treatment outcomes using PRF for intrabony defect regeneration and sites treated with conventional open flap debridement (OFD). Methods: 35 years systematically healthy non-smoker patient diagnosed with chronic periodontitis had generalized intrabony defects on left and right sides of the jaws in molar and premolar area. The defects were diagnosed clinically and radiographically (PD › 5mm, intrabony defect depth › 3mm on the x-ray). Using split-mouth technique, three-wall intrabony defects were treated using PRF one one side of the jaw and with conventional OFD on the other. Radiological control using standardized parallel technique and clinical examination (probing depth (PD), clinical attachment level (CAL), gingival margin level (GML)) were recorded at baseline and 3 months post-operatively. Results: After 3 months intrabony defects treated with PRF demonstrated better clinical and radiographic parameters than the conventional OFD side. PD reduction, CAL gain as well as bone fill measured using standardized radiographs had a tendency to be greater in the defects treated with PRF. Conclusions: The results of the current case report indicate that clinical parameters (PD, CAL, GML) and intrabony defect fill obtained using PRF in this particular case were superior comparing to convetional OFD. However, long-term, randomized, controlled clnical trials are needed to make robust conclusion on PRF effectiveness for intrabony defect treatment.