Influence of intestinal microorganisms on anastomotic leakage after colorectal surgery
| Date |
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2020-11-19 |
Surgery
The Conference is organized by the Student’s Scientific Society of Lithuanian University of Health Sciences The content of the abstract book is redacted. The Student’s Scientific Society of Lithuanian University of Health Sciences did not have control over the abstracts. The authors remain responsible for the content of their respective abstracts. All abstracts presented in the conference were reviewed.
Bibliogr.: p. 99
Introduction One of the most common and serious complications of near-postoperative surgery after right and left hemicolectomy, sigmoid resection, and closure of ileostomy is intestinal leakage with a frequency of 1 to 24%. Therefore, it is very important to evaluate the factors that may determine the development of this complication. One of the etiological factors behind the development of this complication is the intestinal microbiota, which is playing an increasingly important role in this process. Nevertheless, there is still a lack of comprehensive clinical evidence on the influence of the intestinal microbiota on postoperative complications such as anastomotic leakage. Aim To evaluate the influence of intestinal microorganisms on anastomotic leakage after scheduled intestines surgery. Methods A prospective study was performed at the Lithuanian University of Health Sciences Hospital, Kaunas Clinics, Clinic of Surgery. Patients who underwent colon surgery (right hemicolectomy, left hemicolectomy, sigmoid resection and closure of ileostomy) were selected from 01/09/2019 to 01/01/2020. The main criteria for designing the sample were: patients older than 18 years old; anastomosis formed during surgery; scheduled operations; intestines were prepared before surgery. Intestinal mucosal specimens were collected before restoring intestinal integrity and sent for microbiological and antibiotic examination. Patients were also observed postoperatively for signs of near-postoperative complications, particularly anastomotic leakage. Statistical analysis was performed using MS Excel 2010 and SPSS 25.0 packages. Data were considered statistically significant at p <0.05. Results The study involved 50 patients: 22 (44.0 %) males and 28 (46.0 %) females. The majority of patients were treated for colon cancer - 46 (92.0 %), and 4 (8.0 %) for other reasons. There were performed 19 (38.0 %) sigmoid resections, 11 (22.0 %) ... [...].