{"id":49624,"date":"2022-05-12T05:45:16","date_gmt":"2022-05-12T02:45:16","guid":{"rendered":"https:\/\/lsmu.lt\/about-lsmu\/structure\/medical-academy\/faculty-of-pharmacy\/vaistu-chemijos-katedra\/"},"modified":"2024-02-09T08:34:51","modified_gmt":"2024-02-09T06:34:51","slug":"department-of-drug-chemistry","status":"publish","type":"page","link":"https:\/\/lsmu.lt\/en\/about-lsmu\/structure\/medical-academy\/faculty-of-pharmacy\/department-of-drug-chemistry\/","title":{"rendered":"DEPARTMENT OF DRUG CHEMISTRY"},"content":{"rendered":"\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">The University of Lithuania was founded in 1922. At that time, the Faculty of Medicine had four departments, including the Department of Pharmacy. There was only one joint Department of Pharmacy and Pharmacognosy founded and headed for a long time (until 1939) by Prof. Petras Raudonikis. In 1932, following the construction of the building of the Faculty of Medicine (A.Mickevi\u010diaus g. 9), premises for the Department of Pharmacy and Pharmacognosy were completed on the third floor. When Kaunas University was reinstated in 1944, the Department was reorganised and replaced by two specialised departments: the Department of Pharmacy (later renamed the Department of Pharmaceutical Chemistry) and the Department of Botany and Pharmacognosy. The Department of Pharmaceutical Chemistry was headed by Prof. B. \u0160iaulis for a long time, from 1939 until his death in 1957. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In 1957-1972, the Department was headed by Assoc. Prof. V. Brasi\u016bnas, in 1972-1983 \u2013 by Assoc. Prof. E. Tarasevi\u010dius. In 1978-2008, the Department of Pharmaceutical Chemistry and Pharmacognosy was reinstated and headed by Assoc. P. Vainauskas in 1983-1987, Assoc. Prof. F. Malinauskas in 1987-1993, and Prof. V. Janulis in 1993-2008. In 2008, the Department of Pharmaceutical Chemistry and Pharmacognosy was again reorganised into two departments: the Department of Pharmacognosy and Department of Medicinal Chemistry. In 2008-2017, the Department of Drug Chemistry was headed by Prof. H. Rodovi\u010dius. Since 2018, the Department of Drug Chemistry has been headed by Prof. R. Mork\u016bnien\u0117.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Doctoral dissertations were defended by the staff of the Department: E. Tarasevi\u010dius in 1967 (Lviv Medical Institute), R. Bernatoniene in 1977 (Moscow Medical Institute), H. Rodovi\u010dius in 1984 (Kyiv University), F. Malinauskas in 1987 (All-Union Scientific-Research Institute of Drug Chemistry and Technology), V. Brusokas in 1988 (Moscow Institute of Precision Chemical Technology), A. Dagilyt\u0117 in 2001 (Kaunas Medical University), V. Petrikait\u0117 in 2007, R. Benetis in 2009, and A. \u0160padien\u0117 in 2015. E. Tarasevi\u010dius defended his thesis for the degree of Habilitated Doctor at Moscow Medical Academy in 1990.<\/p>\n\n\n<\/div>\n<\/div>\n\n<div class=\"page-content\">\n\n\t<div class=\"container\">\n\t\t\t\t\t<div class=\"prose md:prose-lg\">\n\t\t\t\t<h2>OUR ACTIVITIES<\/h2>\n\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"tabs-h mt-10\">\n\t\t\t\t<ul class=\"js-tabs full-color-tabs\">\n\t\t\t\t                    \t\t\t\t\t\t\t\t\t\t\t<li class=\"current\" id=\"studies\"><a href=\"#tab-01\">STUDIES<\/a><\/li>\n\t\t\t\t\t\t\t\t\t\t                    \t\t\t\t\t\t\t\t\t\t\t<li  id=\"research\"><a href=\"#tab-02\">RESEARCH<\/a><\/li>\n\t\t\t\t\t\t\t\t\t\t                    \t\t\t\t\t\t\t\t\t\t\t<li  id=\"projects\"><a href=\"#tab-03\">PROJECTS<\/a><\/li>\n\t\t\t\t\t\t\t\t\t\t                    \t\t\t\t\t\t\t\t\t\t\t<li  id=\"collaboration\"><a href=\"#tab-04\">COLLABORATION<\/a><\/li>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"tab-c bordered active\" id=\"tab-01\">\n\t\t\t\t\t\t\t<div class=\"prose md:prose-lg\">\n\t\t\t\t\t\t\t\t<h3>Mandatory subjects<\/h3>\n<p><strong>Mandatory courses<\/strong><\/p>\n<p><strong>Integrated study programme &#8220;Pharmacy&#8221;:<\/strong><\/p>\n<ul>\n<li>\u201cPharmacogenomics and Drug Metabolism\u201d for the 3rd year students;<\/li>\n<li>Module \u201cPharmaceutical Chemistry\u201d for the 3rd year students;<\/li>\n<li>Module \u201cDrug Chemistry\u201d for the 4th year students;<\/li>\n<li>Part \u201cQuality of drugs\u201d of the module &#8220;Development of Pharmaceutical Products&#8221; for the 5th year students;<\/li>\n<li>Part \u201cOrganisation and evaluation of practice in drug analysis in pharmacy\u201d of the module &#8220;Professional Practice in Pharmacy&#8221; for the 5th year students;<\/li>\n<li>Final Master&#8217;s thesis for the 4th and 5th year students;<\/li>\n<li>Elective courses: \u201cDevelopment of drug substances\u201d, \u201cInteractions between antibiotics, bacteria and the macro-organism\u201d.<\/li>\n<\/ul>\n<p><strong>First-cycle study programme \u201cMedical and Veterinary Biochemistry\u201d<\/strong>\u00a0(Faculty of Medicine):<\/p>\n<ul>\n<li>\u201cPharmaceutical Biochemistry\u201d for the 3rd year students.<\/li>\n<\/ul>\n<p><strong>Second-cycle joint KTU-LSMU study programme \u201cMedicinal Chemistry\u201d:<\/strong><\/p>\n<ul>\n<li>Part\u00a0 \u201cPharmaceutical Chemistry\u201d of the module &#8220;Pharmacognosy and Pharmaceutical Chemistry\u201d for the 1st year students.<\/li>\n<\/ul>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"tab-c bordered \" id=\"tab-02\">\n\t\t\t\t\t\t\t<div class=\"prose md:prose-lg\">\n\t\t\t\t\t\t\t\t<ul>\n<li>Synthesis, analysis and study of the effects of biologically active compounds on living organisms.<\/li>\n<li><em>In vitro<\/em> development of cell models for the studies of the efficacy of new drugs.<\/li>\n<li>Search and study of plant-derived multifactorial antioxidants.<\/li>\n<li>Studies on the effects of drugs and their metabolites on humans and microbiota.<\/li>\n<\/ul>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"tab-c bordered \" id=\"tab-03\">\n\t\t\t\t\t\t\t<div class=\"prose md:prose-lg\">\n\t\t\t\t\t\t\t\t<p>Research commissioning contract with UAB ProBioSanus: &#8220;Qualitative Analysis of Metabolites of Probiotic Bacteria Bacillus and Lactobacillus sp&#8221; under Priority 1 &#8220;Promotion of Research, Experimental Development and Innovation\u201d of the EU Funds Investment Operational Programme, Measure No. 012.1-MITA-K-824 &#8220;Innovation Vouchers&#8221;. Service period: 01\/09\/2017 to 28\/02\/2018. Value: EUR 4,000.<\/p>\n<p>Cooperation with the framework of project \u201cExosome Application for Targeted Drug Delivery\u201d (EXOTARGET) funded under measure No. 01.2.2-LMT-K-718-01-0036 \u201cTargeted Research in Smart Specialisation Areas\u201d. Implementation period: 2017\u20132022. Project manager: Dr. Aist\u0117 Jekabsone. Project value: EUR 499,872.20. Project implementers: Prof. R. Mork\u016bnien\u0117, PhD student G. Vydmantait\u0117.<\/p>\n<p>Cooperation with the Institute of Pharmaceutical Technologies under Measure No. J05-LVPA-K-01-0248 \u201cIntellect. Joint Science-Business Projects\u201c: \u201cPromotion of UAB Akvavita investments in R&amp;D activities by developing innovative products in the beverage industry\u201d. Project manager Prof. Dr. V. Jak\u0161tas. Project value: EUR 315,887.22. Project implementer: Prof. R. Mork\u016bnien\u0117.<\/p>\n<p>Cooperation under the bilateral research project of Lithuania and Japan by the Neuroscience Institute: \u201cStudy of the molecular determinants of Alzheimer&#8217;s disease: the relationship between extracellular tau, beta amyloid, and neuroinflammation\u201d (INFLAMATAU), the Research Council of Lithuania. Source of funding: the Research Council of Lithuania. Implementation period: 2018\u20132020. Project manager: R. Mork\u016bnien\u0117.<\/p>\n<p>Joint LSMU-KTU project \u201cGeneration of o-Quinone Methides and Investigation Their Conjugates and Metabolites in Saccharomyces Cerevisiae Lag and Log Phases\u201d (CHINONMETIDAS). Project manager: R. Mork\u016bnien\u0117. Project implementer: L. \u0160lepikas. Source of funding: the LSMU Research Fund, 2019.<\/p>\n<p>Cooperation under project No. 01.2.2-LMT- K-718-01-0038 \u201cPoint-of-Care method for ticagrelor pharmacogenomics\u201d (OPTOGEN) jointly funded from the structural funds of the European Union, coordinated by the Institute of Cardiology. Project implementer: V. Tatar\u016bnas. Source of funding: the Research Council of Lithuania, SMART project funds.<\/p>\n<p>Cooperation with UAB SynHet (headed by L. \u0160lepikas) under project No. 01.2.1-LVPA-K-856-01-0188 \u201cDevelopment of high potency compounds against S. aureus based on the in silico chemogenomics, in vitro and in vivo studies\u201d. Implementation period: 2020-2022. Project value: EUR 534,061.00<\/p>\n<p>Cooperation with UAB SynHet (headed by L. \u0160lepikas) under project No. 01.2.2-MITA-K-702-06-0018 \u201cDevelopment of the adaptive robotic separation system\u201d. Implementation period: 2020-2021. Project value: EUR 99,000.<\/p>\n<p>Cooperation under project No. 01.2.2-LMT-K-718-05-0052 \u201cTechnology for the management of COVID-19-induced mitochondrial dysfunction of cardiovascular system\u201d (cTECH) coordinated by the Institute of Cardiology. Project manager: Dr. Aist\u0117 Jekabsone. Project value: EUR 299,965.66. Implementation period: 2021-2023. Project manager: PhD student G. Vydmantait\u0117.<\/p>\n<p>Cooperation with UAB SynHet (headed by L. \u0160lepikas) under project BIOTECH-02-006 \u201cDevelopment of in silico chemogenomics-based biologically active compounds against K. pneumoniae, A. baumannii, P. aeruginosa, and Enterobacter spp.\u201d. Project manager: Liudas Ivanauskas. Project value: EUR 194,793.00.<\/p>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"tab-c bordered \" id=\"tab-04\">\n\t\t\t\t\t\t\t<div class=\"prose md:prose-lg\">\n\t\t\t\t\t\t\t\t<p>Neuroscience Institute of LSMU<\/p>\n<p>Institute of Cardiology of LSMU<\/p>\n<p>Department of Biochemistry of LSMU<\/p>\n<p>Life Sciences Centre<\/p>\n<p>State Medicines Control Agency under the Ministry of Health of the Republic of Lithuania<\/p>\n<p>Kharkiv National University of Pharmacy, Department of Pharmaceutical Chemistry (Ukraine)<\/p>\n<p>Medical University of Bialystok, Department of Pharmaceutical and Bio-Pharmaceutical Analysis (Poland)<\/p>\n<p>Odessa National Medical University, Faculty of Pharmacy (Ukraine)<\/p>\n<p>University of Copenhagen, Department of Neuroscience (Denmark)<\/p>\n<p>University of Tartu, Institute of Pharmacy under the Faculty of Medicine (Estonia)<\/p>\n<p>Houston Methodist Research Institute, Department of Nanomedicine (the U.S.)<\/p>\n<p>Association of the European Self-Medication Industry<\/p>\n<p>Business partners: UAB SynHet, UAB Ferentis, UAB Aconitum<\/p>\n<p>Kopenhagos Universiteto (Danija) Neuromoksl\u0173 departamentas<\/p>\n<p>Tartu universiteto (Estija) Medicinos fakulteto Farmacijos institutas<\/p>\n<p>Hjustono metodist\u0173 mokslo instituto (JAV) Nanomedicinos departamentas<\/p>\n<p>Europos savaranki\u0161k\u0173 vaist\u0173 (Self-Medication) pramon\u0117s asociacija<\/p>\n<p>Verslo partneriai: UAB \u201eSynHet\u201c, UAB \u201eFerentis\u201c, UAB \u201cAconitum\u201c<\/p>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t            <script>\n                var hash = window.location.hash;\n                document.querySelectorAll('.js-tabs li').forEach(function(elm) {\n                    if ( ('#'+ elm.id) === hash) {\n                        document.querySelectorAll('.js-tabs li.current').forEach(function(elm2) {\n                            elm2.classList.remove('current');\n                        });\n                        document.querySelectorAll('.tabs-h .tab-c.active').forEach(function(elm2) {\n                            elm2.classList.remove('active');\n                        });\n\n                        elm.classList.add('current');\n                        var id = elm.querySelector('a').getAttribute('href').replace('#', '');\n                        document.querySelector('.tabs-h #' + id).classList.add('active');\n                    }\n                    elm.addEventListener('click', function(e) {\n                        const url = new URL(window.location);\n                        url.hash = '#'+ elm.id;\n                        window.history.pushState({}, '', url);\n                    });\n                });\n            <\/script>\n\n\t\t\t<\/div>\n<\/div>\n\n<div class=\"container\">\n\t<div class=\"prose md:prose-lg\">\n\n\n<\/div>\n<\/div>\n<div class=\"container\">\n\t\t<ul class=\"doc-links my-6\">\n\t\t\t\t\t                <li>\n                    <a href=\"https:\/\/lsmu.lt\/wp-content\/uploads\/2022\/05\/ma_ff_vaistu-chemijos-katedros_nuostatai.pdf\" download>\n                        <div class=\"icon\">\n                            <svg width=\"36\" height=\"36\"><use xlink:href=\"https:\/\/lsmu.lt\/wp-content\/themes\/lsmu\/images\/icons\/icons.svg#doc\"\/><\/svg>\n                        <\/div>\n                        Regulations of the Department                    <\/a>\n                <\/li>\n\n            \n        \t<\/ul>\n<\/div>\n\n<div class=\"container\">\n\t<div class=\"prose md:prose-lg\">\n\n\n<\/div>\r\n<\/div>\r\n<div class=\"page-content\">\r\n\t<div class=\"container\">\r\n\t\t\r\n\t\t<div class=\"contact-boxes\">\r\n\t\t\t\t\t\t\t\t\t<div class=\"box box-blue\">\r\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"title-b\">\r\n\t\t\t\t\t\t\tDepartment of Drug Chemistry\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t<div class=\"bottom\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"line\">\r\n\t\t\t\t\t\t\t\t<svg width=\"16\" height=\"16\"><use xlink:href=\"https:\/\/lsmu.lt\/wp-content\/themes\/lsmu\/images\/icons\/icons.svg#pin\"\/><\/svg>\r\n\t\t\t\t\t\t\t\tSukil\u0117li\u0173 pr. 13, Kaunas, Lithuania\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t                                                \t\t\t\t\t<\/div>\r\n\t\t\t\t<\/div>\r\n\t\t\t\t\t\r\n\t\t\t\t\t\t\t\t\t<div class=\"box with-image\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"image\">\r\n\t\t\t\t\t\t\t\t<img decoding=\"async\" class=\"bg\" loading=\"lazy\" src=\"https:\/\/lsmu.lt\/wp-content\/uploads\/2022\/05\/TBF_1221.jpg\" alt=\"\">\r\n\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"text-2xl font-semibold\">\r\n\t\t\t\t\t\t\t\tProf. dr. Ramun\u0117 Mork\u016bnien\u0117\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"pb-4 text-lg\">\r\n\t\t\t\t\t\t\t\tDean of the Faculty of Pharmacy\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"bottom\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"tel:+370 37 327 248\" class=\"line\">\r\n\t\t\t\t\t\t\t\t\t\t<svg width=\"16\" height=\"16\"><use xlink:href=\"https:\/\/lsmu.lt\/wp-content\/themes\/lsmu\/images\/icons\/icons.svg#phone\"\/><\/svg>\r\n\t\t\t\t\t\t\t\t\t\t+370 37 327 248\t\t\t\t\t\t\t\t\t<\/a>\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"mailto:ramune.morkuniene@lsmu.lt\" class=\"line\">\r\n\t\t\t\t\t\t\t\t\t\t<svg width=\"16\" height=\"16\"><use xlink:href=\"https:\/\/lsmu.lt\/wp-content\/themes\/lsmu\/images\/icons\/icons.svg#mail\"\/><\/svg>\r\n\t\t\t\t\t\t\t\t\t\tramune.morkuniene@lsmu.lt\t\t\t\t\t\t\t\t\t<\/a>\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t                                \t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t<\/div>\r\n\r\n\t\t\t\t\t\t\r\n\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t<a href=\"https:\/\/kontaktai.lsmuni.lt\/lt\/kontaktai?populate=Vaist%C5%B3+chemijos+katedra\" class=\"btn btn-outline btn-primary btn-lg\"  target=\"_blank\" >All contacts <svg class=\"ml-3\" width=\"48\" height=\"18\"><use xlink:href=\"https:\/\/lsmu.lt\/wp-content\/themes\/lsmu\/images\/icons\/icons.svg#arrow\"\/><\/svg><\/a>\r\n\t\t\t<\/div>\r\n<\/div>\r\n\r\n<div class=\"container\">\r\n\t<div class=\"prose md:prose-lg\">\r\n","protected":false},"excerpt":{"rendered":"<p>The University of Lithuania was founded in 1922. At that time, the Faculty of Medicine had four departments, including the Department of Pharmacy. There was only one joint Department of Pharmacy and Pharmacognosy founded and headed for a long time (until 1939) by Prof. Petras Raudonikis. In 1932, following the construction of the building of [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"parent":17249,"menu_order":836,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-49624","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.1 (Yoast SEO v28.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>DEPARTMENT OF DRUG CHEMISTRY - LSMU<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lsmu.lt\/en\/about-lsmu\/structure\/medical-academy\/faculty-of-pharmacy\/department-of-drug-chemistry\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"DEPARTMENT OF DRUG CHEMISTRY\" \/>\n<meta property=\"og:description\" content=\"The University of Lithuania was founded in 1922. At that time, the Faculty of Medicine had four departments, including the Department of Pharmacy. There was only one joint Department of Pharmacy and Pharmacognosy founded and headed for a long time (until 1939) by Prof. Petras Raudonikis. 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