{"id":52143,"date":"2022-05-09T10:49:09","date_gmt":"2022-05-09T07:49:09","guid":{"rendered":"https:\/\/lsmu.lt\/research-and-innovations\/research-institutes\/kardiologijos-institutas\/laboratorijos\/"},"modified":"2023-08-30T16:01:46","modified_gmt":"2023-08-30T13:01:46","slug":"laboratorijos","status":"publish","type":"page","link":"https:\/\/lsmu.lt\/en\/research-and-innovations\/research-institutes\/institute-of-cardiology\/laboratorijos\/","title":{"rendered":"Laboratories"},"content":{"rendered":"<\/div>\n<\/div>\n\n<div class=\"page-content\">\n\n\t<div class=\"container\">\n\t\t\t\t\t<div class=\"prose md:prose-lg\">\n\t\t\t\t<h2>The Institute of Cardiology has 10 laboratories.<\/h2>\n\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<div class=\"tabs-h md:flex border border-gray-300 mt-10\">\n\t\t\t\t<ul class=\"js-tabs full-v-color-tabs\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<li class=\"current\" id=\"1-cardiac-pathology-laboratory\"><a href=\"#tab-01\">1.\tCARDIAC PATHOLOGY LABORATORY<\/a><\/li>\n\t\t\t\t\t\t\t\t\t        \t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<li  id=\"2-automation-of-cardiovascular-investigation-laboratory\"><a href=\"#tab-02\">2.\tAUTOMATION OF CARDIOVASCULAR INVESTIGATION LABORATORY<\/a><\/li>\n\t\t\t\t\t\t\t\t\t        \t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<li  id=\"3-clinical-cardiology-laboratory\"><a href=\"#tab-03\">3.\tCLINICAL CARDIOLOGY LABORATORY<\/a><\/li>\n\t\t\t\t\t\t\t\t\t        \t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<li  id=\"4-cell-culture-laboratory\"><a href=\"#tab-04\">4.\tCELL CULTURE LABORATORY<\/a><\/li>\n\t\t\t\t\t\t\t\t\t        \t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<li  id=\"5-membrane-biophysics-laboratory\"><a href=\"#tab-05\">5.\tMEMBRANE BIOPHYSICS LABORATORY<\/a><\/li>\n\t\t\t\t\t\t\t\t\t        \t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<li  id=\"6-molecular-cardiology-laboratory\"><a href=\"#tab-06\">6.\tMOLECULAR CARDIOLOGY LABORATORY<\/a><\/li>\n\t\t\t\t\t\t\t\t\t        \t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<li  id=\"7-laboratory-of-population-studies\"><a href=\"#tab-07\">7.\tLABORATORY OF POPULATION STUDIES<\/a><\/li>\n\t\t\t\t\t\t\t\t\t        \t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<li  id=\"8-preclinical-research-laboratory-for-medicinal-products\"><a href=\"#tab-08\">8.\tPRECLINICAL RESEARCH LABORATORY FOR MEDICINAL PRODUCTS<\/a><\/li>\n\t\t\t\t\t\t\t\t\t        \t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<li  id=\"9-laboratory-of-drug-targets-histopathology\"><a href=\"#tab-09\">9. LABORATORY OF DRUG TARGETS HISTOPATHOLOGY<\/a><\/li>\n\t\t\t\t\t\t\t\t\t        \t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<li  id=\"10-laboratory-of-cell-communication\"><a href=\"#tab-010\">10.\tLABORATORY OF CELL COMMUNICATION<\/a><\/li>\n\t\t\t\t\t\t\t\t\t        \t\t\t\t<\/ul>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"tab-c active\" id=\"tab-01\">\n\t\t\t\t\t\t\t<div class=\"prose md:prose-lg smh-2\">\n\t\t\t\t\t\t\t\t<p>Head of the Laboratory<br \/>\n<strong>Prof. Habil. Dr. Dalia Pangonyt\u0117<br \/>\n<\/strong>Phone: +370 37 302 890<br \/>\n<span style=\"color: #000000;\">Email: <a href=\"mailto:dalia.pangonyte@lsmu.lt\">dalia.pangonyte@lsmu.lt<\/a><\/span><\/p>\n<p><span style=\"color: #3366ff;\"><a style=\"color: #3366ff;\" href=\"https:\/\/kontaktai.lsmuni.lt\/lt\/kontaktai?populate=590300\">Laboratory contacts<\/a><\/span><\/p>\n<p><span style=\"color: #333333;\"><strong>Main fields of activity:<\/strong><\/span><\/p>\n<ul>\n<li>Research of the morphological substrate and pathogenesis of acute ischaemic heart disease syndromes.<\/li>\n<li>Studies on the structural expression of ischaemic heart failure.<\/li>\n<\/ul>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"tab-c \" id=\"tab-02\">\n\t\t\t\t\t\t\t<div class=\"prose md:prose-lg smh-2\">\n\t\t\t\t\t\t\t\t<p>Head of the Laboratory<br \/>\n<strong>Prof. Dr. Gediminas Jaru\u0161evi\u010dius<br \/>\n<\/strong>Phone: +370 37 326 094<br \/>\nEmail: <a href=\"mailto:gediminas.jarusevicius@lsmu.lt\">gediminas.jarusevicius@lsmu.lt<\/a><\/p>\n<p><a href=\"https:\/\/kontaktai.lsmuni.lt\/lt\/kontaktai?populate=590400\">Laboratory contacts<\/a><\/p>\n<p><strong>Main fields of activity:<\/strong><\/p>\n<ul>\n<li>Development of cardiology systems for diagnostics, rehabilitation and sports medicine (<em>collaboration with the Lithuanian Sports University, LSMU Faculty of Public Health and LSMU Sports Institute<\/em>).<\/li>\n<li>Assessment of human functional state using the methods of non-linear analysis and complex systems theory (<em>in cooperation with KTU researchers and international partners<\/em>).<\/li>\n<li>\u201cAssessment of the dynamics of cardiovascular system complexity during cardiac interventional procedures (coronary angiography, angioplasty, and bypass surgery)\u201d (<em>collaboration with the KTU researchers and international partners<\/em>).<\/li>\n<li>Development of diagnostic and prognostic algorithms and their application during coronary angioplasty and bypass procedures for evaluation of the success of the procedure and prediction of the long-term prognosis of patient survival and quality of life (<em>collaboration with the researchers of the Department of Physiology of LSMU<\/em>).<\/li>\n<\/ul>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"tab-c \" id=\"tab-03\">\n\t\t\t\t\t\t\t<div class=\"prose md:prose-lg smh-2\">\n\t\t\t\t\t\t\t\t<p>Head of the Laboratory<br \/>\n<strong>Prof. Dr. Egl\u0117 Ereminien\u0117<br \/>\n<\/strong>Phone: +370 37 326 149<br \/>\nEmail: <a href=\"mailto:egle.ereminiene@lsmu.lt\">egle.ereminiene@lsmu.lt<\/a><\/p>\n<p><a href=\"https:\/\/kontaktai.lsmuni.lt\/lt\/kontaktai?populate=590500\">Laboratory contacts<\/a><\/p>\n<p><strong>Main fields of activity:<\/strong><\/p>\n<ul>\n<li>Assessment of prognostic factors of the perioperative period determining respective treatment outcomes in patients with cardiovascular diseases.<\/li>\n<li>Determination of treatment tactics in patients with multiple coronary artery lesions after primary percutaneous coronary intervention: implications for remote outcomes.<\/li>\n<li>Evaluation of the value of myocardial deformability indicators in the detection of myocardial fibrosis in the presence of heart valve malformations.<\/li>\n<li>Associations between depression correction and changes in heart rate variability parameters (state at rest and response to psychological\/arithmetic stress test) in patients after cardiac surgery.<\/li>\n<li>Experimental study of the effect of ultrasonic (cavitation) energies on the function of isolated blood vessels using waveguides of different configurations and power.<\/li>\n<\/ul>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"tab-c \" id=\"tab-04\">\n\t\t\t\t\t\t\t<div class=\"prose md:prose-lg smh-2\">\n\t\t\t\t\t\t\t\t<p>Head of the Laboratory<br \/>\n<strong>Prof. Dr. Vytenis Arvydas Skeberdis<br \/>\n<\/strong>Phone: +370 37 302 880<br \/>\nEmail: <a href=\"mailto:arvydas.skeberdis@lsmu.lt\">arvydas.skeberdis@lsmu.lt<\/a><\/p>\n<p><a href=\"https:\/\/kontaktai.lsmuni.lt\/lt\/kontaktai?populate=590600\">Laboratory contacts<\/a><\/p>\n<p><strong>Main fields of activity:<\/strong><\/p>\n<ul>\n<li>Investigation of the influence of B3-adrenergic receptors and their polymorphisms on the L-type calcium current and contractile force of the human heart <em>(collaboration with the Laboratory of Cellular and Molecular Cardiology, Faculty of Pharmacy, University of Paris XI (Dr Rodolphe Fischmeister)<\/em>.<\/li>\n<li>Investigation of the molecular and genetic mechanisms of short QT syndrome, which can lead to syncope, ventricular tachycardias and sudden death<em> (collaboration with Aarhus University, Denmark<\/em>).<\/li>\n<li>The mechanisms regulating midbody inheritance and its role in cancer cell proliferation and invasiveness (<em>collaboration with the Department of Cell and Developmental Biology, University of Colorado, USA<\/em>).<\/li>\n<li>Stem and cancer cell viability and other properties under stress conditions by chromatography, fluorescence microscopy and electrophysiology<em> (collaboration with the Environmental Research Centre of Vytautas Magnus University and the Institute of Experimental and Clinical Pharmacology of Kiel University (Germany<\/em>).<\/li>\n<\/ul>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"tab-c \" id=\"tab-05\">\n\t\t\t\t\t\t\t<div class=\"prose md:prose-lg smh-2\">\n\t\t\t\t\t\t\t\t<p>Head of the Laboratory<br \/>\n<strong>Habil. Dr. Jonas Jurevi\u010dius<br \/>\n<\/strong>Phone: +370 37 302 877<br \/>\nEmail: <a href=\"mailto:jonas.jurevicius@lsmu.lt\">jonas.jurevicius@lsmu.lt<\/a><\/p>\n<p><a href=\"https:\/\/kontaktai.lsmuni.lt\/lt\/kontaktai?populate=590700\">Laboratory contacts<\/a><\/p>\n<p><strong>Main fields of activity:<\/strong><\/p>\n<ul>\n<li>Investigation of hormonal, metabolic and cell volume-dependent mechanisms of myocardial regulation of ionic currents and compartmentation of signalling systems in cardiac cells.<\/li>\n<li>Investigation of the mechanisms of heart failure, cardiac arrhythmia genesis, hypoxia, ischaemia, reperfusion, antiarrhythmic, and other pharmacological agents in the myocardium.<\/li>\n<li>Investigation of the detection and regulatory mechanisms of cardiac myocyte ion channels, including magnesium-sensitive TRPM6 and TRPM7 channels.<\/li>\n<li>Application of optical techniques to the study of cardiac excitation, arrhythmias, and their mechanisms of occurrence.<\/li>\n<li>Pharmacodynamic and pharmacokinetic studies on <em>Elsholtzia ciliata<\/em> (Vietnamese balm).<\/li>\n<\/ul>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"tab-c \" id=\"tab-06\">\n\t\t\t\t\t\t\t<div class=\"prose md:prose-lg smh-2\">\n\t\t\t\t\t\t\t\t<p>Head of the Laboratory<br \/>\n<strong>Prof. Habil. Dr. Vaiva Lesauskait\u0117<br \/>\n<\/strong>Phone: +370 37 302 874<br \/>\nEmail: <a href=\"mailto:vaiva.lesauskaite@lsmu.lt\">vaiva.lesauskaite@lsmu.lt<\/a><\/p>\n<p><a href=\"https:\/\/kontaktai.lsmuni.lt\/lt\/kontaktai?populate=590800\">Laboratory contacts<\/a><\/p>\n<p><strong>Main fields of activity:<\/strong><\/p>\n<ul>\n<li>Genetic epidemiology of cardiovascular diseases (CVDs) (<em>collaboration with the LSMU Cardiology Clinics and Clinics of Cardiac, Thoracic and Vascular Surgery<\/em>).<\/li>\n<li>Investigation of candidate genes and variants relevant to the morphogenesis of cardiovascular diseases.<\/li>\n<li>Pharmacogenomic studies of cardiovascular diseases (<em>collaboration with the LSMU Cardiology Clinics and Clinics of Cardiac, Thoracic and Vascular Surgery<\/em>).<\/li>\n<\/ul>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"tab-c \" id=\"tab-07\">\n\t\t\t\t\t\t\t<div class=\"prose md:prose-lg smh-2\">\n\t\t\t\t\t\t\t\t<p>Head of the Laboratory<br \/>\n<strong>Prof. Dr. Dalia Luk\u0161ien\u0117<br \/>\n<\/strong>Phone: +370 37 302 892<br \/>\nEmail: <a href=\"mailto:dalia.luksiene@lsmu.lt\">dalia.luksiene@lsmu.lt<\/a><\/p>\n<p><a href=\"https:\/\/kontaktai.lsmuni.lt\/lt\/kontaktai?populate=590900\">Laboratory contacts<\/a><\/p>\n<p><strong>Main fields of activity:<\/strong><\/p>\n<ul>\n<li>Implementation of population-based registries for ischaemic heart disease (acute myocardial infarction) and stroke<em>(collaboration with the Kaunas Clinics of the LSMU Kaunas Hospital, LSMU Kaunas Hospital, Kaunas City Ambulance Station, Kaunas City Polyclinic, Institute of Hygiene)<\/em>.<\/li>\n<li>Epidemiological studies on cardiovascular and other chronic diseases and their risk factors in the adult population<em> (collaboration with the LSMU Faculty of Public Health)<\/em>.<\/li>\n<li>Epidemiological studies on cardiovascular diseases and their risk factors in children and adolescent population<em> (collaboration with Kaunas district municipality, Public Health Burau of Kaunas district municipality).<\/em><\/li>\n<\/ul>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"tab-c \" id=\"tab-08\">\n\t\t\t\t\t\t\t<div class=\"prose md:prose-lg smh-2\">\n\t\t\t\t\t\t\t\t<p>Head of the Laboratory<br \/>\n<strong>Prof. Dr. Edgaras Stankevi\u010dius<br \/>\n<\/strong>Phone: +370 37 327 257<br \/>\nEmail: <a href=\"mailto:edgaras.stankevicius@lsmu.lt\">edgaras.stankevicius@lsmu.lt<\/a><\/p>\n<p><a href=\"https:\/\/kontaktai.lsmuni.lt\/lt\/kontaktai?populate=591200\">Laboratory contacts<\/a><\/p>\n<p><strong>Main fields of activity:<\/strong><\/p>\n<ul>\n<li>Investigation of cardiovascular functions.<\/li>\n<li>Research on medicinal products and drug application models in collaboration with all clinical departments.<\/li>\n<\/ul>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"tab-c \" id=\"tab-09\">\n\t\t\t\t\t\t\t<div class=\"prose md:prose-lg smh-2\">\n\t\t\t\t\t\t\t\t<p>Head of the Laboratory<br \/>\n<strong>Prof. Dr. Vilma Petrikait\u0117<br \/>\n<\/strong>Phone: +370 37 327 316<br \/>\nEmail: <a href=\"mailto:vilma.petrikaite@lsmu.lt\">vilma.petrikaite@lsmu.lt<\/a><\/p>\n<p><a href=\"https:\/\/kontaktai.lsmuni.lt\/lt\/kontaktai?populate=591300\">Laboratory contacts<\/a><\/p>\n<p><strong>Main fields of activity:<\/strong><\/p>\n<ul>\n<li>Investigation of biological effects of substances (antioxidant, antimicrobial, anticancer, antimetastatic, anti-inflammatory, and other activities).<\/li>\n<li>Material permeability studies in 2D and 3D cell cultures.<\/li>\n<li>Development of functionalized nanoformulations for targeted therapies.<\/li>\n<li>Assessment of the effects of hypoxia and pH on cell growth, migration, and invasion.<\/li>\n<li>Assessment of interactions between cell populations.<\/li>\n<\/ul>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"tab-c \" id=\"tab-010\">\n\t\t\t\t\t\t\t<div class=\"prose md:prose-lg smh-2\">\n\t\t\t\t\t\t\t\t<p>Head of the Laboratory<br \/>\n<strong>Dr. Lina Kraujalien\u0117<br \/>\n<\/strong>Phone: +370 37 302 880<br \/>\nEmail: <a href=\"mailto:lina.kraujaliene@lsmu.lt\">lina.kraujaliene@lsmu.lt<\/a><\/p>\n<p><a href=\"https:\/\/kontaktai.lsmuni.lt\/lt\/kontaktai?populate=591400\">Laboratory contacts<\/a><\/p>\n<p><strong>Main fields of activity:<\/strong><\/p>\n<ul>\n<li>Structural-functional studies and biophysical properties of connexin-based gap junctions.<\/li>\n<li>Modelling and experimental studies of cardiac and neural cell networks.<\/li>\n<li>The effect of connexins on the genesis and course of cardiovascular diseases<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><strong>Implemented projects:<\/strong><\/p>\n<p><a href=\"https:\/\/lsmu.lt\/en\/project-study-of-connexin-26-mutations-in-syndromic-deafness\/\">\u201eStudy of connexin 26 mutations in syndromic deafness\u201c<\/a><\/p>\n<p>&nbsp;<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t            <script>\n                var hash = window.location.hash;\n                document.querySelectorAll('.js-tabs li').forEach(function(elm) {\n                    if ( ('#'+ elm.id) === hash) {\n                        document.querySelectorAll('.js-tabs li.current').forEach(function(elm2) {\n                            elm2.classList.remove('current');\n                        });\n                        document.querySelectorAll('.tabs-h .tab-c.active').forEach(function(elm2) {\n                            elm2.classList.remove('active');\n                        });\n\n                        elm.classList.add('current');\n                        var id = 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class=\"wp-block-spacer\"><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":51,"featured_media":0,"parent":52085,"menu_order":948,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-52143","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.1 (Yoast SEO v28.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Laboratories - LSMU<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lsmu.lt\/en\/research-and-innovations\/research-institutes\/institute-of-cardiology\/laboratorijos\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" 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