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  • research article
    Guiné, Raquel P. F.
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    Gonçalves, Joana
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    Florença, Sofia G.
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    Ferreira, Manuela
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    Cardoso, Ana Paula
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    Djekić, Ilija
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    Tarcea, Monica
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    Rumbak, Ivana
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    Matek Sarić, Marijana
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    Černelič-Bizjak, Maša
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    Isoldi, Kathy
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    EL-Kenawy, Ayman
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    Ferreira, Vanessa
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    Klava, Dace
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    Korzeniowska, Małgorzata
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    Vittadini, Elena
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    Leal, Marcela
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    Papageorgiou, Maria
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    Anjos, Ofélia
    Open Agriculture, 2025-06-19, vol. 10, no. 1, p. 1-16

    There are many factors that can influence people’s attitudes towards healthy eating, including personal nature, sociodemographic influences, and lifestyle. This work investigated to what extent the motivations for healthy food consumption are shaped in individuals from different countries. A questionnaire survey was carried out on a sample of 11,919 participants from 16 countries. The results indicated that the strongest motivations for healthy food consumption were related to the perception of consuming healthy food, eating foods rich in vitamins and minerals, allied to food safety and hygiene concerns. Significant differences were found in healthy motivations between countries. Additionally, the sociodemographic variables that had a higher influence on health motivation levels were country, age, and gender. Concerning the anthropometric and lifestyle variables influencing healthy motivation for food consumption, the discriminating variables were: believing in having a healthy diet, physical exercise, and chronic diseases. In conclusion, the work showed important differences in the motivations for a healthy diet in different countries, but other variables also play a role in the motivation for the consumption of foods for health and well-being.

  • research article;
    Advances in Ophthalmology & Visual System, 2025-06-17, vol. 15, no. 2, p. 49-53

    Graves’ ophthalmopathy is associated with a reduced blinking frequency, eyelid retraction, proptosis, incomplete eyelid closure. Smoking significantly increases the incidence and severity of GO in patients with Graves’ disease Objective: To assess the influence of smoking on the development of dry eyes in patients with Graves’ ophthalmopathy (GO) and to determine the properties of tear secretion and ocular surface in these patients. Methods: A cross-sectional study was conducted at the outpatient department of the Eye Diseases Clinic of the Lithuanian University of Health Sciences. The study included 52 patients with a mean age of 47.3 (17.4–69.6) years. The study included 25 smokers and 27 non-smokers with Graves’ ophthalmopathy (a total of 52 patients). Their mean age was 47.3 (17.4–69.6) years. Patients underwent ophthalmological examination, ocular surface disease index (OSDI) assessment, Schirmer test without local anesthesia (<5 mm was abnormal), slit-lamp biomicroscopy (tear break-up time (TBUT) under blue light illumination). Statistical analysis was performed using SPSS for Windows software (SPSS Inc., Chicago, IL, USA). Statistical significance was determined at p < 0.05. Results: The mean OSDI score in smoking GO patients was significantly higher (28.79 ± 15.29) compared to non-smoking patients (10.58 ± 7.41), (p < 0.05). The mean Schirmer test value in smoking GO patients was significantly lower (4.21 ± 3.07 mm) compared to non-smoking patients (11.74 ± 6.24 mm). The difference was statistically significant (p < 0.04), indicating insufficient tear production. The mean tear film breakup time (TBUT) was lower in smoking GO patients (7.04 ± 2.25 s) compared with nonsmoking patients (10.93 ± 3.12 s), ( p < 0.04), indicating an unstable tear film. Conclusion: The study found statistically significantly increased OSDI scores, shorter Schirmer scale and tear film breakup time measurements in smokers with GO. These data may indicate a predisposition to dry eye syndrome in smokers.

  • journal-article;
    Journal of Ophthalmology and Advance Research, 2025-06-01, vol. 6, no. 2, p. 1-8

    Purpose: to determine clinical signs, retinal nerve fiber layer and central macular thickness in patients with Graves ophthalmopathy

    Objectives: To determine the Clinical Activity Score, best visual acuity, intraocular pressure and exophthalmos in patients with Graves’ Ophthalmopathy. To determine Retinal Nerve Fiber Layer (RNFL) and Central Macular Thickness (CMT) by Optical Coherent Tomography (OCT). To determine the relationship between CAS, best visual acuity, intraocular pressure, exophthalmos and RNFL, central macular thickness.

    Methods: The retrospective study was done at Lithuanian University of Health sciences Kaunas Clinic of Eye diseases outpatient department. We reviewed the electronic medical records of all patients with Graves‘ ophthalmopathy seen at the Clinic of Eye diseases between 2021 and 2024, selecting 62 total patients (124 eys). The median age was 49.3 years, ranging from 18.4 years to 74.5 years. All patients had undergone a full ophthalmologic exam, including Best Corrected Visual Acuity (BCVA), Clinical Activity Score (CAS), exophthalmometry with Hertel mirror exophthalmometer, dilated fundus imaging, Schiotz tonometry and OCT imaging (RNFL and CMT).

    All data were processed using statistical analysis software IBM SPSS 29.0. A statistical significance level of p<0.05 was considered.

    Results: The mean of CAS of patients was 3,22 ± 0.43, (range 0-7). The mean BCVA was 0.84 ± 0.19. Intraocular eye pressure ranged form 12.3 to 23.5 mmHg, with a mean of 16.83 ± 2.75 mmHg. Exophthalmos results ranged form 13.9 to 23.3 mm. The mean was 18.26 ± 2.07 mm. The mean of RNFL thickness was 96.84 ± 11.27μm and central macular thickness was 271.43± 22.82μm. A statistically significant correlation was found between BCVA and RNFL, CMT thickness (r=0.376, p=0.001, r=0.258, p=0.026, respectively). A statistically significant negative correlation was found between CAS and RNFL, CMT (r=-0.406, p<0.001; r=-0.233, p=0.046, respectively). These data indicate that the lower the visual acuity and the higher the disease activity, the thinner the RNFL and CMT.

    A negative significant correlation was between IOP, exophthalmos and RNFL (r=-0.348, p=0.002; r=-0.287, p=0.013, respectively). This shows that the greater IOP and exophthalmos the thinner RNFL. However, there was no significant relationships between IOP, exophthalmos and CMT (r=-0.14, p=0.235; r=-0.2, p=0.088, respectively).

    Conclusion: A statistically significant correlation was found between Clinical activity score, best corrected visual acuity, intraocular pressure, exophthalmos and RNFL in patients with GO. CAS and BCVA were significantly correlated with central macular thickness. There was no significant relationship between IOP, exophthalmos and CMT. Our study suggests that OCT is useful in diagnosing, monitoring and predicting vision in patients with compressive optic neuropathy in GO.

  • research article;
    Journal of Ophthalmology and Advance Research, 2025-06-02, vol. 6, no. 2, p. 1-6

    The aim of our study was to evaluate the features of Graves’ ophthalmopathy in juvenile Graves disease.

    Objectives: To identify the signs of Graves’ ophthalmopathy in juvenile patients with Graves’ disease.

    Methods: The retrospective study was done at the Lithuanian University of Health science Kaunas Clinic of Eye diseases outpatient department. We reviewed the electronic medical records of all patients with Graves‘ Disease (GD) seen at the Clinic of Eye diseases, selecting 130 total patients, the age at diagnosis of GD, patients age was 17 (4.4-29.3) years. All patients had undergone a full ophthalmologic exam, including visual acuity, CAS, exophthalmometry with Hertel mirror exophthalmometer, biomicroscopy and ophthalmoscopy.

    The statistical analysis was performed using the following softtware program package „SPSS for Windows“ (SPSS Inc., Chicago, IL, USA). The level of statistical significance was set at p<0.05 for all the tests.

    Results: Of the total 130 patients with GD, 92 had no evidence of Graves’ Ophthalmopathy (GO-) and 38 had Graves’ Ophthalmopathy (GO+). When comparing the development of Graves’ Ophthalmopathy in patients with Graves’ disease by gender, we found that in both (GO+ and GO-) groups, there were statistically significantly more females than males (76.3/23.7% in the GO +group and 91.3/8.7% in the GO- group, p < 0.05). The study found that 38 patients with Graves’ disease had ocular changes characteristic of Graves’ Ophthalmopathy. The most common patient’s complaints were bulging of eyes (76.3%) and symptoms which are characteristic of dry eye syndrome (eye grittiness – 42.1%, tearing – 42.1% and photophobia – 31.6%). In the Graves’ ophthalmopathy group, the most common specific signs were upper eyelid retraction (73.7%) and Graefe’s symptom (47.4%). As non-specific, clinical symptoms of activity, showing 42.1 % of cases, hyperemia of conjunctivae (42.1%), carunculal redness (23.7%) were observed. The clinically active form (CAS was more than 3 points out of 7) was observed in 8 (21.1%) GO+ patients. 8 (21.1%} patients had impaired eye movements, but eye movements were limited only to the lateral side. There were no color sensitivity disorders in GO+ patients.

    Conclusion: The most common patient’s with Graves’ Ophthalmopathy complaints were bulging of eyes and symptoms which are characteristic of dry eye syndrome (eye grittiness, tearing and photophobia). In this group of patients the most common specific signs were upper eyelid retraction and Graefe’s symptom. As non-specific, clinical symptoms of Graves’ Ophthalmopathy activity were hyperemia of conjunctivae, carunculal redness.

  • review article;
    Poderiene, Kristina
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    Potyazhenko, Maksim
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    Mintser, Ozar
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    Frontiers in Systems Neuroscience, 2025-06-23, vol. 19, p. 1-23

    This perspective piece presents the concept of the role and mechanisms of cells’ electromagnetic communication. These data deepen the scientific understanding of the fundamental aspects of the phenomenon of human life. A promising model of biophoton signaling as a scientific tool for further developing of biophotonics of the human body is substantiated.

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  • journal article
    Lietuvos bendrosios praktikos gydytojas. Kaunas : Vitae Litera, 2008, t. 12, Nr. 10., p. 679-681.

    Lėtinis atrofinis gastritas – tai ilgalaikio lėtinio skrandžio uždegimo sąlygota skrandžio gleivinės atrofija. Atrofinio gastrito fone vystosi metaplazija žarninio tipo epiteliu, vėliau epitelio displazija ir skrandžio vėžys. Atrofija ir žarninė metaplazija apibūdinamos kaip ikivėžinės būklės. Skrandžio gleivinės atrofija ir žarninė metaplazija yra dažnesnės šalyse, kuriose yra didelis sergamumas skrandžio vėžiu. Atrofinis gastritas laikomas ikivėžine liga, tačiau nėra visiškai aišku, ar galimas atrofijos proceso sustabdymas, ar tai leidžia apsaugoti nuo skrandžio vėžio.

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