Keratocistų chirurginio gydymo galimybės

Baromand Rad, Suzanne

Use this url to cite ETD: https://hdl.handle.net/20.500.12512/101165

Evaluation of the Keratocystic Odontogenic Tumor (KCOT) recurrence after different treatment modalities

Type of publication

type::text::thesis::master thesis

Title

Evaluation of the Keratocystic Odontogenic Tumor (KCOT) recurrence after different treatment modalities

Other Title

Keratocistų chirurginio gydymo galimybės

Author

Baromand Rad, Suzanne

Advisor

Keizeris, Tadas

Other(s)

Guzevičienė, Vesta	Recenzentas / Reviewer
Janužis, Gintaras	Recenzentas / Reviewer
Guzevičienė, Vesta	Komisijos narys / Committee Member
Sakavičius, Dalius	Komisijos narys / Committee Member
Lukošiūnas, Algirdas	Komisijos narys / Committee Member
Gervickas, Albinas	Komisijos narys / Committee Member
Bojarskas, Stasys	Komisijos narys / Committee Member

Extent

30 p.

Thesis Defence Date

2017

Keywords (lt)

Odontogenic Keratocys...

Treatment method

Marsupialization

Enucleation

Keratocyst recurrence...

Keratocistų

Gydymo būde

Marsupialization

Enucleation

Keratocistų pasikarto...

Abstract (lt)

The aim of this systematic review is: to determine the most optimal treatment method when treating KCOT and pinpoint the potential factors that contribute to the high RR. Study objectives are the following:

Review current treatment methods and their potential cause for recurrence. 2. Look closer at the contributing factors that cause recurrence and how and if they can be prevented. 3. Analyse all types of KCOTs and classifications of their severity. [4,14] The hypothesis of this study is that the RR is dependant on treatment modality and that the clinician can affect factors that contribute to the recurrence. Purpose: To understand the correlation between the recurrence rates of the Keratocystic odontogenic tumors (KCOT) with different treatment modalities used to treat the lesion. Materials and Method: A systematic review. Items for Systematic reviews PRISMA guidelines were performed. An extensive search in a major university search motor Chalmers, including major databases such as Science Direct and PubMed, was performed to include all articles of relevance. Articles selected were adapted using the PICOS components the following inclusion criteria: Published studies, cohort studies, prospective randomized controlled clinical trials, prospective or retrospective clinical studies, prospective and retrospective reviews, case series with regard to various treatment modalities and recurrence rate. Results: Resection is the only treatment modality that has displayed a 0% recurrence rate (RR) and also the treatment modality correlated with the highest morbidity. Cryotherapy and Carnoy’s solution in combination with enucleation has proven to have similar effects as resection and has displayed a decrease in RR to 2%. Potential reasons for recurrence; epithelial remnants left postoperatively, involvement of surrounding vital structures and size and location has shown heterogeneity in their significance to cause recurrence. Conclusion: Keratocystic odontogenic tumour is a very aggressive cyst and is widely recognized for its high recurrence rate. A definitive and optimal treatment method is still not agreed upon nor is there an agreement upon all aspects that may contribute to the recurrence of the KCOT. There is a clear lack of published evidence in this matter.

Abstract (en)

Šio sistemingai peržiūros tikslas: nustatyti optimaliausią gydymo būdą, gydant KCOT ir tiksliai nustatyti galimus veiksnius, kurie prisideda prie aukšto RR. Studijų tikslai yra šie:

Peržiūrėkite dabartinė gydymo metodai ir jų potencialas priežastis pasikartojimo. 2. Peržiūrėk arčiau prie prisidedančių veiksnių, kurie sukelia pasikartojimui ir kaip ir jei jie gali būti užkirstas kelias. 3. Analizuoti visus KCOTs ir klasifikacijų jų sunkumo tipus. [4,14] Šio tyrimo hipotezė yra, kad RR yra priklausoma nuo gydymo metodas ir kad gydytojas gali paveikti veiksnius, kurie prisideda prie pasikartojimo.