Publication: Efficacy and Tolerability of Topiramate / M. Endziniene, N. Vaiciene, G. Jurkeviciene, J. Grigoniene, L. Gumbeleviciute, L. Lukosiute
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Date
2005-08-28
Authors
Endzinienė, Milda
Vaičienė, Nerija
Jurkevičienė, Giedrė
Laurynaitienė, Jūratė
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Abstract
Purpose: To investigate the efficacy and tolerability of topiramate (TPM) in refractory childhood epilepsy. Methods: The information about the effects of TPM was collected with the help of a questionnaire filled in by the parents of 66 children with refractory epilepsy. Clinical data were retrieved from medical charts of the patients at Kaunas University Hospital. Results: Mean duration of epilepsy was 64.3 months. Positive effects were observed in 53 (80.3%) cases, with more than 50% seizure reduction in 64%; in 20% it was temporary. [...].
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Keywords
Epilepsy, Epilepsy, Anticonvulsants, Fructose