Investigation of Certain General Anesthetic Agents and Their Combination Influence on Animal Erythrocyte and Brain Tissue
Author(s) | |
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Kučinskas, Kęstutis |
Date Issued |
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2011-09-22 |
Common anesthetic agents and their undesirable side effects in the organism is a relevant topic in Cymbopogon.y, the emergence of anesthetic- induced adverse reaction mechanisms are insufficiently clear, however important, as they determine the essential and vital functions of stability and homeostasis. One in the animal's organism, the anesthetics are readily fat-solube thereby affecting various tissues, cells at their molecular levels which easily penetrate the phospholipid membranes of cell organelles and can cause irreversible infringements - cell apoptosis. The purpose was to determine how various general anesthetic agents and their combinations affect different animal erythrocyte membranes and their brains. The study was carried out in 2010-2011. An investigation was performed on the influence of ketamine, midazolam, diazepam and their combinations (via intravenous injection) on the horse, cow, pig, cat and dog erythrocytes, followed by and ketamine, midazolam, isoflurane, sevoflurane and their combinations on the mouse and rabbit brain. Blood samples were tested at the LSMU VA Pathology Centre. [...].