Serological markers for the diagnosis of acute mesenteric arterys ischaemia. A review of literature

Abstract

Introduction Intestinal ischaemia, in particular due to acute thrombo-embolic occlusion of the mesenteric arterys, is associated with high total mortality. Although, even experienced clinicians find it difficult to diagnose the patients quickly enough to permit timely intestinal revascularisation before it progressed from intestinal ischaemia to necrosis. Still, it remains a challenging problem linked to the lack of reliable diagnostic biochemical tools, which would be realistically.pathognomonic for this life threatening condition. With this research, we set out to determine and find which serological markers could be used for diagnosis of acute mesenteric arterys ischaemia. Aim To resarch, analyse and evaluate the scientific literature about available serological markers for the diagnosis of acute mesenteric arterys ischaemia. Objectives 1. Research and identify, what kind of serological markers could be used for the diagnosis of acute mesenteric artery ischaemia. 2. Research and identify, which serological markers could be practical for the diagnosis of acute mesenteric artery ischaemia in the routine clinical practice. Methods The research of scientific literature was performed using these data bases: Pubmed, Science direct, Springerlink, EBSCO publishing. These key words were used for the search: markers for the diagnosis of acute mesenteric artery ischaemia (AMAI), biomarkers of acute mesenteric artery thrombosis, acute mesenteric artery ischaemia, diagnosis of mesenteric ischaemia, mesenteric artery infarction. We reviewed 42 publications from 2001 till 2015 years and 26 of them, in which serological markers in humans for the diagnosis of AMAI thoroughly discussed, were selected for further analysis, rejecting studies wit[...].