Body mass index association with chronic atrophic gastritis

Abstract

INTRODUCTION.The development of chronic atrophic gastritis (CAG) is multifactorial. Studies suggest, that higher body mass index (BMI) is associated with development of CAG [1,2]. AIM To assess potential interaction of the association between body mass index (BMI) with chronic atrophic gastritis (CAG). METHODS In total 58 patients, who underwent gastroscopy (>18 years), were enrolled in the study. Gastric biopsies were taken to evaluate hystological changes. Patients were divided into four groups based on their body mass index (BMI): less than 18,5; 18,5-24,99; 25-29,99; 30 and more. The risk of AG with increasing BMI was analyzed. Statistical data analysis was performed with statistical program SPSS 22.0 (Statistical Package for Social Sciences) and Microsoft Office Excel 2010. To compare results Chi-Square test was used. Differences were considered as statistically significant when p< 0,05. RESULTS 14 (21,1%) of participants were males and 44 (75,9%) were females. The mean age was 40,48 years (SD±13.636, min. 22, max. 68). 51,7% of the patients had normal BMI (18,5 - 24,99); 34,5% were overweighed (25-29,99); 8,6% were obese (≥30) and 5,2% had insufficient body mass index (<18,5). 65,5% (No. 38) of patients were diagnosed with chronic gastritis. The mean BMI was higher in patients with chronic gastritis in comparison with those, who did not have chronic gastritis (M=24,55, SD±3,43 versus M=23,11, SD±4,37), but no statistically significant difference was reached (p>0,05). Gastric atrophy was found in 24,13% (No.14) of patients. Mostly gastric atrophy was diagnosed in patients with normal BMI in comparison with overweighed patients group (85,7% vs. 14,3%, p=0,031).[...].