Use this url to cite publication: https://hdl.handle.net/20.500.12512/238045
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Phenolic Compounds of Rhodiola rosea L. as the Potential Alternative Therapy in the Treatment of Chronic Diseases
Type of publication
Straipsnis Web of Science ir Scopus duomenų bazėje / Article in Web of Science and Scopus database (S1)
Title
Phenolic Compounds of Rhodiola rosea L. as the Potential Alternative Therapy in the Treatment of Chronic Diseases
Publisher (trusted)
Date Issued
2023-07-31
Is part of
International Journal of Molecular Sciences
Version
Originalus / Original
Description
Art. no. 12293.
This article belongs to the Special Issue The Effect of Phenolic Compounds in Human Diseases
Volume
24
Issue
15
Start Page
1
End Page
17
Field of Science
OECD Classification
Abstract
The roots and rhizomes of Rhodiola rosea L. (Crassulaceae), which is widely growing in Northern Europe, North America, and Siberia, have been used since ancient times to alleviate stress, fatigue, and mental and physical disorders. Phenolic compounds: phenylpropanoids rosavin, rosarin, and rosin, tyrosol glucoside salidroside, and tyrosol, are responsible for the biological action of R. rosea, exerting antioxidant, immunomodulatory, anti-aging, anti-fatigue activities. R. rosea extract formulations are used as alternative remedies to enhance mental and cognitive functions and protect the central nervous system and heart during stress. Recent studies indicate that R. rosea may be used to treat diabetes, cancer, and a variety of cardiovascular and neurological disorders such as Alzheimer's and Parkinson's diseases. This paper reviews the beneficial effects of the extract of R. rosea, its key active components, and their possible use in the treatment of chronic diseases. R. rosea represents an excellent natural remedy to address situations involving decreased performance, such as fatigue and a sense of weakness, particularly in the context of chronic diseases. Given the significance of mitochondria in cellular energy metabolism and their vulnerability to reactive oxygen species, future research should prioritize investigating the potential effects of R. rosea main bioactive phenolic compounds on mitochondria, thus targeting cellular energy supply and countering oxidative stress-related effects.
Is Referenced by
Type of document
type::text::journal::journal article::research article
ISSN (of the container)
1661-6596
1422-0067
WOS
001046317900001
Other Identifier(s)
PMCID: PMC10418374
Coverage Spatial
Šveicarija / Switzerland (CH)
Language
Anglų / English (en)
Bibliographic Details
140
Affiliation(s)
Date Reporting
2023
Creative Commons License
Journal | IF | AIF | AIF (min) | AIF (max) | Cat | AV | Year | Quartile |
---|---|---|---|---|---|---|---|---|
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 5.6 | 6.4 | 5.9 | 6.9 | 2 | 0.896 | 2022 | Q1 |
Journal | IF | AIF | AIF (min) | AIF (max) | Cat | AV | Year | Quartile |
---|---|---|---|---|---|---|---|---|
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 5.6 | 6.4 | 5.9 | 6.9 | 2 | 0.896 | 2022 | Q1 |
Journal | Cite Score | SNIP | SJR | Year | Quartile |
---|---|---|---|---|---|
International Journal of Molecular Sciences | 7.8 | 1.263 | 1.154 | 2022 | Q1 |