Generic medications in ophthalmology

Abstract

Introduction 1 What is a Generic Drug? 1.1 Definition of generic drug, the pharmacokinetics, pharmacodynamics, and bioequivalence 1.2 The regulatory approach to generic drugs 2 History of Generic Drugs 2.1 History of drug legislation in the United States 2.2 History of generic drugs in Europe 3 Various Perceptions and Perspectives on Generic Drugs 3.1 Patient's perspectives 3.1.1 Geographical variability 3.1.2 Socio-economic variability 3.1.3 Causes of poor patient acceptance 3.2 Impact of poor patient acceptance 3.3 Physician's perspectives 3.4 Pharmacist's perspectives 4 Comparison of Generic to Branded Drugs 4.1 Comparison of generic to branded systemic drugs 4.2 Concerns regarding generic ophthalmic drugs 4.3 Factors affecting bioavailability in the eye 4.4 Drug penetration barriers 4.5 Comparison of generic to branded ophthalmic drugs 4.6 Generic drugs in glaucoma 5 The Issue of Cost 5.1 The impact of generic medication 5.2 Medicare and Medicaid 6 The Future of Generic Drugs References .