Repeated measures of heavy metals content in organism of children with alopecia after the zinc supplementation

Abstract

The imbalance of trace elements had have been induced by the replacements of essential elements with toxic heavy metals may lead to the disturbances of zinc metabolism and consequently may cause the deficiency of this element. The zinc deficiency may trigger the onset of hair loss disease in children or other sensitive population groups beside the rest factors. The aim of this continuous research was to monitor the changes of heavy metals concentration in children (n=17) with hair loss disease of various degree after the treatment with zinc supplementation. The repeated measures showed the tendencies of toxic heavy metals (lead and cadmium) content decrease due to zinc supplementation in organism of children with alopecia while significant decrease merely for blood lead level was established (p<0.05). The data showed hair zinc content increase along with declined zinc excretion though the organism saturation with zinc was insignificant. Furthermore, few cases of hair regrowth in those children observed. The effectiveness of zinc supplementation in certain children alopecia treatment was demonstrated though it requires further investigations.