Pan-European registry on H. Pylori management (HP-EUREG): bacterial resistance of 2241 H. Pylori isolates
| Author | Affiliation |
|---|---|
McNicholl, Adrian Gerald | |
Introduction: Antibacterial resistance is the major cause of failed eradication attempts in the management of H. pylori infection. Aims & Methods: We aimed to evaluate the resistance rates encountered by European gastroenterologists in their routine clinical practice A Local Coordinator was selected from each country with more than 10 H. pylori references in PubMed. Each Coordinator selected a representative group of recruiting investigators from his/her country. An e-CRF was created on AEG-REDCap to systematically register all adult patients infected with H. pylori. Variables included: H. pylori diagnostic test used, use of culture and susceptibility testing methods, or molecular tests for the evaluation of antibiotic resistance. Results: So far 20, 175 patients have finished follow-up. Culture was performed in 12% of cases: 2241 isolates of which 1878 are first-line. Table shows antibiotic resistance (% and 95% CI) per antibiotic and line of treatment .Introduction: Antibacterial resistance is the major cause of failed eradication attempts in the management of H. pylori infection. Aims & Methods: We aimed to evaluate the resistance rates encountered by European gastroenterologists in their routine clinical practice A Local Coordinator was selected from each country with more than 10 H. pylori references in PubMed. Each Coordinator selected a representative group of recruiting investigators from his/her country. An e-CRF was created on AEG-REDCap to systematically register all adult patients infected with H. pylori. Variables included: H. pylori diagnostic test used, use of culture and susceptibility testing methods, or molecular tests for the evaluation of antibiotic resistance. Results: So far 20, 175 patients have finished follow-up. Culture was performed in 12% of cases: 2241 isolates of which 1878 are first-line. Table shows antibiotic resistance (% and 95% CI) per antibiotic and line of treatment...