Use this url to cite publication: https://hdl.handle.net/20.500.12512/87891
Gap19 inhibits connexin-43 hemichannels without inhibiting gap junctions and limits cardiac ischemia
Type of publication
Konferencijų tezės nerecenzuojamame leidinyje / Conference theses in non-peer-reviewed publication (T2)
Author(s)
| Author | Affiliation |
|---|---|
De Vuyst, Elke | |
Title
Gap19 inhibits connexin-43 hemichannels without inhibiting gap junctions and limits cardiac ischemia
reperfusion injury in mice / De Vuyst Elke, Wang Nan1, Ponsaerts Raf, Boengler Kerstin, Abudara Veronica, Palacios-Prado Nicolas, Wauman Joris, Lai Charles P., De Bock Marijke, Decrock Elke, Bol Melissa, Leurs Kirsten, Vinken Mathieu, Rogiers Vera, Tavernier Jan, Evans W. Howard, Naus Christian C., Bukauskas Feliksas F., Giaume Christian, Heusch Gerd, Schulz Rainer, Bultynck Geert, Leybaert Luc
Publisher (trusted)
Universiteit Gent
Date Issued
| Date |
|---|
2011-08-06 |
Extent
p. 220, no. 10.10.
Is part of
International Gap Junction Conference : August 6-11, 2011, Ghent - Belgium : [Abstracts. Posters] / Universiteit Gent ; Org. committee: Christian Giaume, Luc Leybaert [et al.]. Ghent : Universiteit Gent, 2011.
Version
Originalus / Original
Series/Report no.
Abstracts from poster session 3.
Abstracts from poster session 3.
Field of Science
Abstract (en)
Connexins form gap jungtion (GJs) that connect the cytoplasm of neighboring cells and unapposed/nonjunctional hemichannels that form a patway for the exchange of ions and metabolities between the cytoplasm and the extracellular milieu. Blocking hemichannels may enchance cell survival by preventing ionic imbalance, cell swelling and loss of critical metabolites. However, currently known hemichannel inhibitors also block GJ channels, thereby disturbing electrical and metabolic cell-cell communication. [...].
Type of document
type::text::conference output::conference proceedings::conference paper
Other Identifier(s)
(LSMU ALMA)990000764490107106
Coverage Spatial
Belgija / Belgium (BE)
Language
Anglų / English (en)