Tractional retinal detachment in proliferative diabetic retinopathy as complication of experimental treatment

Abstract

Introduction: One of diabetes mellitus complications is diabetic retinopathy. In diabetic retinopathy. In its proliferative stage neovascular vessels grow on optic nerve disc and over major retinal vessels. As the neovascularisation progresses fibrous tisue grows and follows it. Fibrovascular meshwork becomes extensive and adherent to the posterior hyaloid face. Leakage from new vessels and alterations of the blood-retinal barrier lead to hemorrhages into vitreous, its contraction and tractional retinal detachment. Mild vitreous hemorrhages resorb spontaneously and cause short vision reduction only, while retinal detachment in macular region reduces vision reduction only, while retinal detachment in macular region reduces vision until vitrectomy and fibrovascular membrane removal release retina. Despite neovascularisation progression responds well to novel antiVEGF treatment, it is crucial to know, that those agents cause contraction of fibrous membranes and increase risk of retinal detachmentCase report: 46 years old female was diagnosed with type 2 diabetes mellitus 23 yeras ago. [...].