Use this url to cite publication: https://hdl.handle.net/20.500.12512/111772
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The Effect of Ozone Treatment on the Physicochemical Properties and Biocompatibility of Electrospun Poly(ε)caprolactone Scaffolds / Lauryna Dabasinskaite, Edvinas Krugly, Odeta Baniukaitiene, Dainius Martuzevicius, Darius Ciuzas, Lina Jankauskaite, Lauryna Aukstikalne, Arvydas Usas
Type of publication
Straipsnis Web of Science duomenų bazėje / Article in Web of Science database (S1a)
Author(s)
Dabašinskaitė, Lauryna | Kauno technologijos universitetas |
Krugly, Edvinas | Kauno technologijos universitetas |
Baniukaitienė, Odeta | Kauno technologijos universitetas |
Martuzevičius, Dainius | Kauno technologijos universitetas |
Čiužas, Darius | Kauno technologijos universitetas |
Title
The Effect of Ozone Treatment on the Physicochemical Properties and Biocompatibility of Electrospun Poly(ε)caprolactone Scaffolds / Lauryna Dabasinskaite, Edvinas Krugly, Odeta Baniukaitiene, Dainius Martuzevicius, Darius Ciuzas, Lina Jankauskaite, Lauryna Aukstikalne, Arvydas Usas
Publisher (trusted)
Multidisciplinary Digital Publishing Institute (MDPI AG)
Date Issued
2021-08-18
Extent
p. 1-18.
Is part of
Pharmaceutics. Basel, Switzerland : MDPI, 2021, vol. 13, no. 8.
Version
Originalus / Original
Description
art.no. 1288.
OA, (CC BY) license.
Field of Science
Abstract
Ozonation has been proved as a viable surface modification technique providing certain properties to the scaffolds that are essential in tissue engineering. However, the ozone (O3) treatment of PCL scaffolds in aqueous environments has not yet been presented. O3 treatment performed in aqueous environments is more effective compared with traditional, executed in ambient air treatment due to more abundant production of hydroxyl radicals (•OH) within the O3 reaction with water molecules. During interaction with •OH, the scaffold acquires functional groups which improve wettability properties and encapsulate growth factors. In this study, a poly(ε)caprolactone (PCL) scaffold was fabricated using solution electrospinning and was subsequently ozonated in a water reactor. The O3 treatment resulted in the expected occurrence of oxygen-containing functional groups, which improved scaffold wettability by almost 27% and enhanced cell proliferation for up to 14 days. The PCL scaffold was able to withhold 120 min of O3 treatment, maintaining fibrous morphology and mechanical properties.
Is Referenced by
Type of document
type::text::journal::journal article
ISSN (of the container)
1999-4923
WOS
000690068600001
Other Identifier(s)
(LSMU ALMA)990001043530107106
Coverage Spatial
Šveicarija / Switzerland (CH)
Language
Anglų / English (en)
Bibliographic Details
75
Funding(s)
Funding(s) | Project ID |
---|---|
European Regional Development Fund | 01.2.2-LMT-K-718 |
Journal | IF | AIF | AIF (min) | AIF (max) | Cat | AV | Year | Quartile |
---|---|---|---|---|---|---|---|---|
Pharmaceutics | 6.525 | 4.805 | 4.805 | 4.805 | 1 | 1.358 | 2021 | Q1 |
Journal | IF | AIF | AIF (min) | AIF (max) | Cat | AV | Year | Quartile |
---|---|---|---|---|---|---|---|---|
Pharmaceutics | 6.525 | 4.805 | 4.805 | 4.805 | 1 | 1.358 | 2021 | Q1 |
Journal | Cite Score | SNIP | SJR | Year | Quartile |
---|---|---|---|---|---|
Pharmaceutics | 6 | 1.364 | 0.922 | 2021 | Q2 |