Nutraceutical Modelling the Gastrointestinal Microbiota and Response of the Immune System
Author(s) | ||
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Juodeikienė, Gražina | Kauno technologijos universitetas | |
Žadeikė, Daiva | Kauno technologijos universitetas | |
Viškelis, Pranas | Lietuvos agrarinių ir miškų mokslų centras | |
Date Issued |
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2021-10-22 |
Abstracts. Scientists Section
ISBN 978-9955-15-711-3
Bibliogr.: p. 19
Introduction: Prevention of sub-clinical infections also as the modulation of probiotic bacteria in gut can be managed by multifunctional nutraceuticals. Lactic acid bacteria (LAB) also as the herbal by-products, essential oils and colostrum, can favourably alter the host immune system and gut microbiota (1), however, their cumulative effect as multicomponent nutraceutical supplement has not been investigated. Materials and methods: The composition includes dehydrated lactic acid bacteria, fermented and lyophilized bovine colostrum, dehydrated apple pomace, oregano extract, mint essential oil, and thyme essential oil. In vivo experiment was conducted on 4 groups of piglets (2) Results: It was observed a statistically significant effect on populations of B lymphocyte, monocyte, T memory cell and Tc cell populations after 28 days of product administration. The studies showed that the nutraceutical also influenced the positive modulation of gut microbiota which resulted in 1.78 times higher number of probiotic strains (Bifidobacterium, Streptococcus, Faecilbacterium). Conclusions: This study shows a purposive effect of the nutraceutical composition on the changes of gut microbiota and response of the immune system.
Funding(s) | Grant No |
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European Regional Development Fund | No 01.2.2- LMT-K-718-01-0062 |
Research Council of Lithuania (LMTLT). | No 01.2.2- LMT-K-718-01-0062 |