Resting and hyperaemic collateral flow for correction of microvascular resistance
Author | Affiliation |
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Boerhout, Coen K.M. | |
Date |
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2022-05-17 |
Background. Collateral flow is thought to significantly influence the invasive measurement of minimal microvascular resistance. Consequently, the need for wedge-pressure measurements to correct for collateral flow hampers its widespread use. Recently, a novel-method to calculate coronary wedge-pressure corrected IMR without the need for balloon-inflation was introduced by Yong et al. This method is not yet validated in a doppler-derived population and importantly, the impact of difference between resting and hyperemic physiological conditions was not accounted for. Objectives/Methods We sought to validate the calculation method for wedge-pressure corrected HMR and evaluate the impact of different physiological conditions on this measurement. Results/Conclusions. Our formula for calculated Pw-corrected HMR was similar to that of Yong et al. There was a significant difference between resting and hyperemic conditions. HMR not-corrected correlated well with both calculated and measured Pw-corrected HMR when hyperemic conditions were applied. [...].