Use this url to cite publication: https://hdl.handle.net/20.500.12512/12953
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Nano-hydroxyapatite/cellulose composite scaffold for bone tissue engineering / O. Petrauskaite, J. Liesiene, C. Santos, P.S. Gomes, M. Garcia, M.H. Fernandes, M.M. Almeida, M.E.V. Costa, G. Juodzbalys, P. Daugela
Type of publication
Tezės Web of Science duomenų bazėje / Theses in Web of Science database (T1a1)
Author(s)
Petrauskaitė, Odeta | Kauno technologijos universitetas |
Liesienė, Jolanta | Kauno technologijos universitetas |
Santos, Catarina | Polytechnic Institute of Setúbal, EST, Portugal |
Gomes, Pedro de Sousa | University of Porto, Porto, Portugal |
Garcia, Mónica Pereira | Laboratory of Pharmacology and Cellular Biocompatibility, Faculty of Dental Medicine, University of Porto, Porto, Portugal |
Fernandes, Maria Helena Raposo | Laboratory of Pharmacology and Cellular Biocompatibility, Faculty of Dental Medicine, University of Porto, Porto, Portugal |
Almeida, Maria Margarida | Department of Ceramic and Glass Engineering, CICECO, University of Aveiro, Aveiro, Portugal |
Costa, Maria Elisabete Jorge Vieira | Department of Materials and Ceramic Engineering, CICECO, University of Aveiro, Aveiro, Portugal |
Title
Nano-hydroxyapatite/cellulose composite scaffold for bone tissue engineering / O. Petrauskaite, J. Liesiene, C. Santos, P.S. Gomes, M. Garcia, M.H. Fernandes, M.M. Almeida, M.E.V. Costa, G. Juodzbalys, P. Daugela
Publisher (trusted)
Is Referenced by
Date Issued
Date Issued |
---|
2012-09-05 |
Extent
p. 34, no. 04.P15.
Is part of
Journal of Tissue Engineering and Regenerative Medicine : 3rd TERMIS World Congress : September 5-8, 2012, Vienna, Austria : abstract book / Editor-in-Chief: Rui L. Reis. Chichester, West Sussex, UK : John Wiley & Sons, 2012, vol. 6, suppl. 1, September.
Version
Originalus / Original
Series/Report no.
04. Hypertrophic Cartilage and Bone Tissue Engineering.
Field of Science
Abstract
Bone engineering via synthetic biomaterials implies the interplay of various agents including a synthetic scaffold, bone progenitor cells and growth factors. To perform successfully the ideal scaffold should be a 3D interconnected porous structure promoting cell adhesion, proliferation and vascularisation and allowing bioactive substances to be supplied to incorporated or ingrown cells. The present work explores the preparation and characterization of cellulose/hydroxyapatite composite structures for bone tissue regeneration in maxillofacial region and their osteoblastic cytocompatibility. Cellulose/hydroxyapatite porous scaffolds were produced by freeze drying suspensions of cellulose and chemically synthesized hydroxyapatite nanoparticles. Experimental parameters including cellulose concentration, pre-lyophilisation condition, and hydroxyapatite nanoparticle morphology were used to manipulate scaffold porosity, micron- and nano-scale topography. The biological characterization of cellulose/hydroxyapatite composites was conducted with MG-63 human osteoblastic-cells. The obtained freezedried bodies are highly porous, with pore size ranging from micron to nanometric scale. Furthermore, assayed composites revealed improved biological profile, by enhancing the adhesion, poliferation and functional activity of seeded osteoblastic-like cells. Attained results substantiate the suitable application of cellulose//hydroxyapatite scaffolds in bone tissue engineering applications.
Type of document
type::text::conference output::conference proceedings::conference paper
ISSN (of the container)
1932-6254
Other Identifier(s)
(LSMU ALMA)990000797660107106
Coverage Spatial
Austrija / Austria (AT)
Language
Anglų / English (en)
Journal | IF | AIF | AIF (min) | AIF (max) | Cat | AV | Year | Quartile |
---|---|---|---|---|---|---|---|---|
Journal of Tissue Engineering and Regenerative Medicine | 2.826 | 4.3 | 2.869 | 5.734 | 4 | 0.716 | 2012 | Q1 |
Journal | IF | AIF | AIF (min) | AIF (max) | Cat | AV | Year | Quartile |
---|---|---|---|---|---|---|---|---|
Journal of Tissue Engineering and Regenerative Medicine | 2.826 | 4.3 | 2.869 | 5.734 | 4 | 0.716 | 2012 | Q1 |
Journal | Cite Score | SNIP | SJR | Year | Quartile |
---|---|---|---|---|---|
Journal of Tissue Engineering and Regenerative Medicine | 5 | 0.845 | 1.138 | 2012 | Q1 |