Use this url to cite publication: https://hdl.handle.net/20.500.12512/13225
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Modernization of traditional poly-combination herbal medicinal product: development and validation of HPLC assay of the common markers quercetin, luteolin and emodin / Valdas Jakštas, Audronis Lukošius, Konradas Vitkevičius, Liudas Ivanauskas
Type of publication
Tezės kitame recenzuojamame leidinyje / Theses in other peer-reviewed publication (T1e)
Title
Modernization of traditional poly-combination herbal medicinal product: development and validation of HPLC assay of the common markers quercetin, luteolin and emodin / Valdas Jakštas, Audronis Lukošius, Konradas Vitkevičius, Liudas Ivanauskas
Publisher (trusted)
Lietuvos sveikatos mokslų universitetas |
Date Issued
Date Issued |
---|
2012-11-24 |
Extent
p. 18-19.
Is part of
Achievements and development perspectives of pharmaceutical chemistry and other sciences : the international conference on pharmaceutical sciences and pharmacy practice dedicated to 125th Birth Anniversary of prof. Benediktas Šiaulis : book of abstracts : November 24, 2012 Kaunas, Lithuania / conference organizers : Vitalis Briedis, Eduardas Tarasevičius, Vilma Petrikaitė et al. ; Lithuanian University of Health Sciences. Kaunas : Lietuvos sveikatos mokslų universitetas, 2012. ISBN 978-9955-15-254-5.
Version
Originalus / Original
Series/Report no.
Short talks.
Description
Bibliogr.: p. 19
Field of Science
Abstract
Trejos devynerios is a traditional herbal medicinal product with its origins going back to the times of the Both Nations Republic (1). This preparation was mentioned in the article Wiadomosci farmaceutycsne by prof. J. Muszynski in 1927 (2). In the 20th century, during the Soviet period, Trejos devynerios also known as ,trojanka’ was produced in Kaunas Pharmacy of Medicinal Herbs, in Poland company Herbapol produced ,Trojanka litewska’, in Chicago Lithuanian pharmacists working in J&J pharmacy, also labelled the similar polyingredient mixture as ,Trejos devynerios’ (3). Formula of this traditional phytopreparation includes 27 herbal drugs: poplar buds, capsicum, clove, oak bark, calendula flower, laurel leaf, peppermint leaf, dill fruit, hawthorn berries, wormwood, fragrant pepper, lovage root, valerian root, hop strobilus, bitter-orange epicarp and mesocarp, frangula bark, willow bark, caraway fruit, birch buds, meadowsweet, St. John's wort, hyssop, yarrow, thyme, tormentil rhizome, rowan berries, dog rose hip. Long-time use of this poly-ingredient preparation substantiates its phytotherapeutic properties; however, the substantial increase of quality requirements for herbal medicinal products brings new challenges to pharmaceutical science. The aim of the work: to select quality indicating common markers for assaying of product and to validate HPLC analytical method. Complexity of combination herbal medicinal product makes it difficult and, sometimes, impossible to give analytical identification and quantitative evaluation of the medicinal substances in the product (4). In these situations, with respect to scientific knowledge, application of combined markers, such as aglyconic fragments of various biologically active glycosidic forms is expedient. Hydrolysis of flavonoids and anthracene glycosides to aglycones is included in analytical method of the complicated product that contains 27 medicinal substances of plant origin. To optimise the analytical
Type of document
type::text::conference output::conference proceedings::conference paper
ISBN (of the container)
978-9955-15-254-5
Other Identifier(s)
(LSMU ALMA)990000804180107106
Coverage Spatial
Lietuva / Lithuania (LT)
Language
Anglų / English (en)