Use this url to cite publication: https://hdl.handle.net/20.500.12512/15235
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Binding of bile acids by cellulose-based cationic adsorbents / Jurgita Kazlauske, Kristina Ramanauskiene, Jolanta Liesiene
Type of publication
Straipsnis Web of Science duomenų bazėje / Article in Web of Science database (S1a)
Author(s)
Kazlauskė, Jurgita | Kauno technologijos universitetas |
Liesienė, Jolanta | Kauno technologijos universitetas |
Title
Binding of bile acids by cellulose-based cationic adsorbents / Jurgita Kazlauske, Kristina Ramanauskiene, Jolanta Liesiene
Publisher (trusted)
Academia Republicii Socialiste Romania
Date Issued
2014-01-02
Extent
p. 11-17.
Is part of
Cellulose chemistry and technology. Bucharest : Academia Republicii Socialiste Romania, 2014, vol. 48, no. 1-2.
Version
Originalus / Original
Field of Science
Abstract
One of the ways to regulate the cholesterol level in the blood is by adsorption of overproduced bile acids from the gastrointestinal tract. For this purpose, synthetic anion exchangers have been in clinical use for many years. The efficiency of these sorbents is rather low, because of their low binding capacity. In this work, cationic cellulose derivatives of different structure were evaluated as sorbents for binding of bile acids. It was found out that adsorption of bile acids is highly affected by pH. This was explained taking into account dissociation constants of the bile acids, as well as of the functional groups of the adsorbents. It has been showed that the cellulose-based adsorbents are more effective bile acid binders than the commercial ones, due to their more accessible structure. Comparing cellulosic adsorbents, the macroporous adsorbent DEAE-Granocel in all cases showed the best sorption capabilities.
Is Referenced by
Type of document
type::text::journal::journal article
ISSN (of the container)
0576-9787
Other Identifier(s)
(LSMU ALMA)990000849440107106
Coverage Spatial
Rumunija / Romania (RO)
Language
Anglų / English (en)
Bibliographic Details
24
Journal | IF | AIF | AIF (min) | AIF (max) | Cat | AV | Year | Quartile |
---|---|---|---|---|---|---|---|---|
CELLULOSE CHEMISTRY AND TECHNOLOGY | 0.675 | 1.335 | 1.335 | 1.335 | 1 | 0.506 | 2014 | Q3 |
Journal | IF | AIF | AIF (min) | AIF (max) | Cat | AV | Year | Quartile |
---|---|---|---|---|---|---|---|---|
CELLULOSE CHEMISTRY AND TECHNOLOGY | 0.675 | 1.335 | 1.335 | 1.335 | 1 | 0.506 | 2014 | Q3 |
Journal | Cite Score | SNIP | SJR | Year | Quartile |
---|---|---|---|---|---|
Cellulose Chemistry and Technology | 1.7 | 0.81 | 0.462 | 2014 | Q3 |