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The Course of juvenile Graves’ disease in patients with or without clinical features of Graves’ ophthalmopathy / Jarusaitiene D., Jankauskiene J
Type of publication
Konferencijų tezės nerecenzuojamame leidinyje / Conference theses in non-peer-reviewed publication (T2)
Title
The Course of juvenile Graves’ disease in patients with or without clinical features of Graves’ ophthalmopathy / Jarusaitiene D., Jankauskiene J
Publisher (trusted)
European Society of Ophthalmology
Date Issued
2017-06-10
Extent
p. 91-91, no. EP-EXT-302.
Is part of
Congress of the European Society of Ophthalmology (SOE 2017) : 10-13 June, 2017, Barcelona, Spain : abstract e-book / European Society of Ophthalmology. Barcelona : European Society of Ophthalmology, 2017.
Version
Originalus / Original
Series/Report no.
Electronic poster presentations.
Electronic poster presentations.
Field of Science
Keywords
Abstract
Purpose: To compare the course of Graves’ disease (GD) in patients with Graves’ ophthalmopathy (GO) - GO+ group, or without clinical features of GO - GO- group. Method: A total of 130 patients with juvenile Graves’ disease were investigated over the period of 10 years. The median age at GD diagnosis was 18 (12-20) years. GO symptoms occurred in 38 (29.2%) of GD patients.There were evaluated data about the course of the disease: duration of the first course of the treatment, remission time, relapse rate and duration to compare between groups. Results: GO has occurred an average of 1 month from GD diagnosis, minmax values (0-24 months). Ocular symptoms occurred together with GD diagnosis in 84.4 % of GO patients. Analyzing the effectiveness of juvenile GD treatment, we can see that remission from the first attack was achieved within 14,0 months (9.25 to 24,0), of the group of GO- patients, while in patients GO+ group, remission was achieved within 33 (26-40) months of treatment. Relapses in the first 2 years manifested in 60,5% of GO+ group, and in 38,0% of GO- group patients (p = 0,019). The remission longer than one year was observed in 58,7% and 38,0% in GO- and GO+ groups respectively (p = 0,003). Only single attack without relapses of GD occured in 5.3% of GO+ patients group, whereas 40.2% in GO- group (p< 0,001) during the observation period. Conclusion: It was established that a more severe course of Graves’ disease (more frequent relapses, shorter duration of remission, a longer time to achieve euthyrosis) in patients with Graves’ ophthalmopathy compared with patients in the group without clinical signs of ophthalmopathy.The symptoms of Graves´ ophthalmopathy mostly manifest in the beginning of juvenile Graves´ disease.
Type of document
type::text::conference output::conference proceedings::conference paper
Other Identifier(s)
(LSMU ALMA)990000934120107106
Coverage Spatial
Ispanija / Spain (ES)
Language
Anglų / English (en)