Use this url to cite publication: https://hdl.handle.net/20.500.12512/89408
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18F-FDG PET/CT and contrast-enhanced CT in a one-stop diagnostic procedure: a better strategy for management of patients suffering from retroperitoneal fibrosis? / Renaud Guignard, Marija Simukoniene, Valentina Garibotto, Osman Ratib
Type of publication
Straipsnis Web of Science duomenų bazėje / Article in Web of Science database (S1a)
Author(s)
Guignard, Renaud | Department of Nuclear Medicine, University Hospital of Geneva, Geneva, Switzerland |
Garibotto, Valentina | Department of Nuclear Medicine, University Hospital of Geneva, Geneva, Switzerland |
Ratib, Osman | Department of Nuclear Medicine, University Hospital of Geneva, Geneva, Switzerland |
Title
18F-FDG PET/CT and contrast-enhanced CT in a one-stop diagnostic procedure: a better strategy for management of patients suffering from retroperitoneal fibrosis? / Renaud Guignard, Marija Simukoniene, Valentina Garibotto, Osman Ratib
Publisher (trusted)
Date Issued
2012-05-01
Extent
p. 453-459.
Is part of
Clinical nuclear medicine. Philadelphia : Lippincott, Williams & Wilkins, 2012, vol. 37, no. 5, May.
Version
Originalus / Original
Series/Report no.
Original articles
Field of Science
Abstract
Purpose: Effective management of patients affected by retroperitoneal fibrosis (RPF) is an important issue because of lack of relevant parameters to objectively assess the degree of inflammation. We evaluated added value of contrast-enhanced computed tomography (CE-CT) combined with fluorine-18 fluorodeoxyglucose positron emission tomography (FDG PET) as a one-stop diagnostic procedure for the assessment and follow-up of patients with RPF. Materials And Methods: (18)F-FDG PET and CE-CT findings were reviewed in 10 patients suffering from RPF. Maximum standard uptake values (on native and contrast-enhanced [ESUV(max)] CT) were calculated. Dimensions of periaortitis were measured on CT scans. Observed clinical changes between baseline PET scan (T0) and at 6 months follow-up (T6) were analyzed regarding differences of initial values for clinic and paraclinic parameters. Results: Patients still suffering from pain 6 months after baseline PET scan had initially higher FDG uptake (ESUV(max): 5.7 ± 0.9 vs. 2.4 ± 0.9, P < 0.01). Unlike biologic and CT parameters, FDG uptake was the most relevant parameter to measure severity of inflammation (ESUV(max) threshold: 4.3; Se = Sp = 1.0). CE-CT exclusively allowed better delineation and more accurate assessment of FDG uptake of periaortitis and its extension to adjacent structures. Conclusions: Our results clearly show the usefulness of PET/CT for better evaluation and management of patients with fibroblast proliferation disease. Accurate determination of inflammation level is significantly improved when PET/CT and CE-CT are performed in the same study and used for better delineation of areas of residual inflammation.
Is Referenced by
Type of document
type::text::journal::journal article
ISSN (of the container)
0363-9762
WOS
000302752200015
Other Identifier(s)
(LSMU ALMA)990000795110107106
Coverage Spatial
Jungtinės Amerikos Valstijos / United States of America (US)
Language
Anglų / English (en)
Bibliographic Details
31
Journal | IF | AIF | AIF (min) | AIF (max) | Cat | AV | Year | Quartile |
---|---|---|---|---|---|---|---|---|
CLINICAL NUCLEAR MEDICINE | 2.955 | 2.815 | 2.815 | 2.815 | 1 | 1.05 | 2012 | Q1 |
Journal | IF | AIF | AIF (min) | AIF (max) | Cat | AV | Year | Quartile |
---|---|---|---|---|---|---|---|---|
CLINICAL NUCLEAR MEDICINE | 2.955 | 2.815 | 2.815 | 2.815 | 1 | 1.05 | 2012 | Q1 |
Journal | Cite Score | SNIP | SJR | Year | Quartile |
---|---|---|---|---|---|
Clinical Nuclear Medicine | 1.3 | 0.698 | 0.437 | 2012 | Q3 |