Use this url to cite publication: https://hdl.handle.net/20.500.12512/91410
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In-situ measurements of bacteria resistance to antimicrobial agents employing retractometric method based on sub-wavelength diffraction grating / T. Juknius, T. Tamulevičius, I. Gražulevičiūtė, I. Klimienė, A.P. Matusevičius, S. Tamulevičius
Type of publication
Recenzuojamos išplėstinės tezės / Peer-reviewed extended theses (T1d)
Author(s)
Kauno technologijos universitetas | |
Tamulevičius, Tomas | Kauno technologijos universitetas |
Gražulevičiūtė, Ieva | Kauno technologijos universitetas |
Tamulevičius, Sigitas | Kauno technologijos universitetas |
Title
In-situ measurements of bacteria resistance to antimicrobial agents employing retractometric method based on sub-wavelength diffraction grating / T. Juknius, T. Tamulevičius, I. Gražulevičiūtė, I. Klimienė, A.P. Matusevičius, S. Tamulevičius
Publisher (trusted)
Technologija |
Date Issued
Date Issued |
---|
2013-08-27 |
Extent
p. 43, no. P11 : pav.
Is part of
Advanced Materials and Technologies : Book of abstracts of the 15-th International Conference–School Advanced Materials and Technologies : 27-31 August 2013, Palanga, Lithuania / Kaunas University of Technology. [Lithuanian Materials Research Society. Vilnius Gediminas Technical University et al. ; Organizing Committee: S. Tamulevičius, et al.]. Kaunas : Technologija, 2013.
Version
Originalus / Original
Series/Report no.
Poster presentations.
Poster presentations.
Description
Bibliogr.: p. 43
Field of Science
Abstract
Testing of drug efefctiveness is one of the most important subjects in pharmacy. The purpose of this study was to investigate the possibility to observe Gram-positive bacteria Staphyloccocus aureus wall changes using different amounts of antimicrobial agent benzylpenicillin (500,000 v.v/ml) in real time. Optical method based on total internal reflection in a sub-wavelength diffraction grating was employed. The proposed optical method is sensitive for the eefective refractive index changes in vicinity of a diffraction grating. The results obtained employing optical method were verified compraring results obtained employing standard microbiology tests and bacteria visualization employing Scanning electron microscopy (SEM). Bacterial solution (8.8 billion/ml S. aureus in 0.9% saline solution) was placed in the temperature controlled measurement cell. Different amounts of benzylpenicillin where injected in the measurement cell and changes of the optical signature where monitored in-vitro for the same durations of time. Samples for microbiology tests and SEM analysis were taken from liquid cell after injection of antimicrobial agent. [...].
Type of document
type::text::conference output::conference proceedings::conference paper
ISSN (of the container)
1822-7759
Other Identifier(s)
(LSMU ALMA)990000835850107106
Coverage Spatial
Lietuva / Lithuania (LT)
Language
Anglų / English (en)