Use this url to cite publication: https://hdl.handle.net/20.500.12512/93967
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Cellulose-based grafts for bone regeneration / O. Baniukaitiene, J. Liesiene, A. Palaveniene, G. Juodzbalys, P. Daugela, M. Pranskunas
Type of publication
Straipsnis recenzuojamoje Lietuvos tarptautinės konferencijos medžiagoje / Article in peer-reviewed Lithuanian international conference proceedings (P1e)
Author(s)
Baniukaitienė, Odeta | Kauno technologijos universitetas |
Liesienė, Jolanta | Kauno technologijos universitetas |
Palavenienė, Alisa | Kauno technologijos universitetas |
Title
Cellulose-based grafts for bone regeneration / O. Baniukaitiene, J. Liesiene, A. Palaveniene, G. Juodzbalys, P. Daugela, M. Pranskunas
Publisher (trusted)
Technologija |
Date Issued
Date Issued |
---|
2015-11-26 |
Extent
p. 19-22 : pav.
Is part of
Biomedical Engineering - 2015 : Proceedings of 19th International conference : [Kaunas, Lithuania, 26-2 November 2015] / Kaunas University of Technology. Biomedical Engineering Institute. Lithuanian Society of Biomedical Engineering. Kaunas : Technologija, 2015.
Version
Originalus / Original
Description
Bibliogr.: p. 22
Field of Science
Abstract
In this work cellulose scaffolds with embedded hydroxyapatite particles were prepared. The results obtained in this work revealed that the morphology of composite scaffolds is suitable for bone tissue regeneration. The highly porous scaffolds comprised non-symmetrical interconnected pores. Such arrangement of the pores is essential for cellular activity, in-growth of blood vessels and formation of bone tissue. Moreover, reinforced cellulose scaffolds have demonstrated improved mechanical properties. Introduction. Nowadays various bone grafting materials as autografts, allografts, xenografts and synthetic biomaterials are used for bone tissue regeneration. Autografts are the gold standard for this purpose, since they are osteogenic, osteoinductive and osteoconductive. HOwever, transplantation of autograft tissue requires a second surgical site. This problem is avoided using allograft tissue, taken from another person or xenograft, taken from another species. However, these are generally associated with disease transmission. The synthetic bioceramic materials often agglomerate after implantation and blood vessels cannot grow in. Such constructs should be removed. Three-dimensional (3D) scaffolds fabricated from polymers can be an alternative option for bone regeneration. Synthetic biodegradable polymers as poly(ε-caprolactone) (PCL), poly(glycolic acid) (PGA), poly(lactic acid) (PLA) and (poly(lactic-co-glycolic) acid (PLGA) are the most frequently used materials for the fabrication of 3D scaffolds. In order to improve the mechanical stability of such constructs and enhance bioactivity, several materials, such as hydroxyapatite, β-tricalcium phosphate or bioactive glass are embedded in polymer-based frameworks. The aim of this work was to prepare 3D natural polymer-based scahholds with hydroxyapatite particles for bone tissue regeneration. [...].
Type of document
type::text::conference output::conference proceedings::conference paper
ISSN (of the container)
2029-3380
Other Identifier(s)
(LSMU ALMA)990000886950107106
Coverage Spatial
Lietuva / Lithuania (LT)
Language
Anglų / English (en)
Bibliographic Details
7