Association of cataract with hyperglycemia and smoking in men aged 50-64 years

Abstract

The aim of this study was to estimate the association of cataract with hyperglycemia and cigarette smoking in men aged 50-64 years from Kaunas urban population. Subject and methods. In this work we have used data of 300 men aged 50-64 years from Kaunas city population cohort investigated according to MONICA study protocol during 2001-2002. Cataract was defined by color photography using LOCS III method. Information on smoking habits was obtained with the use of a standard questionnaire. Glucose concentration was determined in capillary blood by individual glucometer. Hyperglycemia was evaluated as fasting glucose ≥6.1 mmol/l. Results. The rate of cataract among 50-64 years men with hyperglycemia was higher than among men without hyperglycemia (38.5% vs. 26.4%; OR was 1.74 (95% CI, 0.94-3.23)). The rate of cataract among former smokers was higher than among current smokers men (40.5% vs. 27.7%; OR was 1.78 (95% CI, 0.92-3.43)) and significantly higher than among never-smokers (40.5% vs. 22.9%; OR was 2.3 (95% CI, 1.16-4.59)). The rate of cataract among smokers (current and former) was 1.44 times higher than among never-smokers (33.0% vs. 22.9%; OR was 1.66 (95% CI, 0.93-2.98)). In comparing of cataract in men aged 50-64 years according hyperglycemia and smoking habits the rate of cataract was significantly higher in smokers (current and former) with hyperglycemia versus never-smokers without hyperglycemia (42.2% vs. 21.2% OR was 2.72 (95% CI, 1.15-6.46). In conclusion, hyperglycemia and smoking habits (current and former) as risk factors of many pathologies are associated with increasing of risk of cataract for 50-64 years urban men.