Lithuanian University of Health Sciences Research Management System (CRIS)
 

Publication:
Histamine releasing action of calcium ionophore 985-I

Simple item page
cris.virtual.orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.author-orcid45303fe5-e204-4354-87e3-e62070d1e0f5
cris.virtualsource.department45303fe5-e204-4354-87e3-e62070d1e0f5
cris.virtualsource.orcid45303fe5-e204-4354-87e3-e62070d1e0f5
dc.contributor.authorGushchin, Igor S.
dc.contributor.authorZebrev, Alexander I.
dc.contributor.authorVoitenko, Valentina
dc.coverage.spatialCH
dc.date.issued1988-04-01
dc.description.abstractThe polyether antibiotic 985-I induced histamine release from rat and mouse mast cells and human basophils. Histamine release induced by low concentrations (10-50 microM) of the ionophore was a selective (noncytotoxic) process. It was energy and Ca2+-dependent and was potentiated by glucose. In this respect the mode of action of 985-I was similar to that of the Ca2+-ionophore A23187. On the other hand some pharmacological agents (phencarol, verapamil and amitriptyline) inhibited histamine secretion induced by 985-I but not A23187-induced histamine release. These data point to some differences between the mechanisms of action of 985-I and A23187.en
dc.description.sponsorshipLietuvos sveikatos mokslų universitetas (302536989)
dc.description.statementofresponsibilityI.S. Gushchin, A.I. Zebrev, V.G. Voitenkoen
dc.description.versionOriginalus / Original
dc.format.extentp. 161-164.
dc.identifier.other(LSMU ALMA)990000291370107106
dc.identifier.pmid2455977
dc.identifier.udc615.37
dc.identifier.urihttps://hdl.handle.net/20.500.12512/48503
dc.language.isoen
dc.relation.ispartofAgents and actions. , 1988, vol. 23, no. 3-4.
dc.relation.isreferencedbyMEDLINE (PubMed)
dc.relation.issn0065-4299
dc.subjectImunologija.en
dc.subject.classificationStraipsnis kitoje duomenų bazėje / Article in other database (S4)
dc.subject.otherMedicina / Medicine (M001)
dc.titleHistamine releasing action of calcium ionophore 985-I
dc.typetype::text::journal::journal article::research article
dcterms.subjectMedicinos ir sveikatos mokslai / Medical and health sciences (M)
dspace.entity.typePublication
local.titleHistamine releasing action of calcium ionophore 985-I / I.S. Gushchin, A.I. Zebrev, V.G. Voitenko
localcerif.author.code#PLACEHOLDER_PARENT_METADATA_VALUE#
localcerif.author.code#PLACEHOLDER_PARENT_METADATA_VALUE#
localcerif.author.code302536989
localcerif.pages4*
localcerif.title.contributorI.S. Gushchin, A.I. Zebrev, V.G. Voitenko
oairecerif.author.affiliationInstitute of Immunology, Russian Federal Medico-Biological Agency, Moscow, Russia
oairecerif.author.affiliationInstitute of Immunology, All-Union Research Institute of Antibiotics, Moscow, USSR
oairecerif.author.affiliationLietuvos sveikatos mokslų universitetas (302536989)

Files

License bundle

Now showing1 - 1 of 1
Loading...
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed to upon submission
Description:
Download

Collections

1. Universiteto mokslo publikacijos / University Research Publications