Starevičius, Danielius

The aim of this study was to evaluate the impact of pegbovigrastim administration in dairy cows on the white blood cells, postpartum diseases, production and reproduction performance. This master thesis was prepared in the department of the Large Animal Clinic of Lithuanian University of Health Sciences (LUHS) in Kaunas, Lithuania. Two large scale dairy farms with a loose holding system from the southern part of Lithuania were included in the study. A number of totally 156 cows were included in the study, the included cows were examined before and after parturition in different ways. The 156 cows were divided into three different groups, treated in different ways pegbovigrastim was administered one alternatively two times and for comparison purposes a non-treated control group was included for examination. Blood samples were collected one week prepartum, the day following parturition and one week postpartum. The blood parameters were evaluated by focusing on the distribution and changes in concentration of WBC´s divided into GRAN, LYMPH and MONO. The postpartum related diseases were followed during the first 30 days in milk (DIM) measured by the incidence rate of mastitis, metritis and retained placenta. The production was studied in terms of milk yield during the first 100 DIM, conception rate and days open. The culling rate in the different groups was also studied. The study revealed that the cows receiving pegbovigrastim developed a lower incidence rate of mastitis and retained placenta contrary a higher incidence rate of metritis compared to non-treated cows. Cows treated with pegbovigrastim produced more milk during the first 100 DIM compared to non-treated cows. The study also revealed that the reproduction improved with decreased days open and increased conception rates. The culling rate was lower in treated cows compared to non-treated cows. Notable is that from treated cows the one that got culled did so in an earlier phase compared to the ones in the non-treated group. Comparing the groups that received one respectively two injections of pegbovigrastim it was seen for the majority of parameters investigated that it was more beneficial to receive two injections.

Aukšto produktyvumo karvių sveikatingumas ir produktyvumas tampriai susijęs su optimalia energijos apykaita. Ketoniniai kūnai, atsirandantys dėl, neigiamo energijos balanso, neigiamai veikia karvių reprodukcines savybes ir primilžį Šio tyrimo tikslas buvo palyginti primilžį, reprodukcinių ligų pasireiškimą ir apsivaisinimą taikant ilgalaikę ir trumpalaikę ketozės prevenciją. Propilenglikolis buvo naudojamas trumpalaikei, monenzinas ilgalaikei profilaktikai. Tyrimas buvo atrinktos 54 karvės, kurioms buvo suduotos pasirinktos medžiagos. Apibendrinant, primilžis padidėjo sudavus monensiną. Tyrimas parodė, kad propilenglikolis, kuris suduodamas iškart po vaisiaus atvedimo, labiau pagerina apsivaisinimą ir sumažina reprodukcines ligas nei monensinas.