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Retrospective analysis of the causes of acute bleeding from the gastrointestinal tract when red blood cell transfusions are necessary
Date Issued |
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2015-05-06 |
Bibliogr.: p. 121
Introduction Acute bleeding (AB) from the gastrointestinal tract (GIT) is one of the most threatening gastroenterological conditions where urgent decisions are needed. Despite the range of reasons for extensive bleeding from the GIT, the principles of their correction are similar: stopping the bleeding and recovery of blood loss volume. Though the principles of bleeding from GIT are obvious, the mortality rate due to this reason still reaches 3-14% [1]. Red blood cell transfusions (RBCT) are carried out in the most serious acute gastrointestinal bleeding cases when the hemoglobin (Hb) content is less than 80 g/L and in cases of unstable hemodynamic (UH). It is therefore purposeful to find out the most life-threatening causes of bleeding, requiring RBCT. Knowing these reasons can be helpful to save time when planning the strategy of management. Aim To analyze the causes of acute bleeding from the gastrointestinal tract, where red blood cell transfusions are necessary. Objectives 1. To identify the most common acute bleeding (AB) causes, when red blood cell transfusions (RBCT) are necessary. 2. To identify and compare the levels of hemoglobin (Hb) among the causes of AB. 3. To determine the cause of AB which required the greatest amount of red blood cells (RBC) and to determine the mean amount of RBC which was transfused to one patient, considering the cause of AB. 4. To identify the mean rise of Hb level after RBCT. 5. To identify the most common causes of AB inducing hemodynamic instability. 6. To evaluate mortality of patients with AB who required RBCT. Methods We analysed 169 medical histories of patients who underwent AB from GIT and were treated with RBCT at Hospital of Lithuanian University of Health Sciences Kaunas Clinics, clinic of Gastroenterology in 2013. The demographic (gender, age), medical data (causes of AB, level of Hb, treatment outcomes, hemodynamic stability) and 318 RBCT protocols of the pat[...].