Options
Right ventricular function in patients with dilated cardiomyopathy of different ethiology
Date Issued |
---|
2007-10-05 |
Lent.
The aim of our study was to assess changes of right ventricular function in patients (pts) with ischaemic and non ischaemic dilated cardiomyopathy and severely depressed left ventricular (LV) systolic function ( LV EF<35%) and to determine whether RV function is associated with clinical status of the pts. Methods and results: Fifty three patients with LV EF<35% were analyzed. Non ischaemic dilated cardiomyopathy was diagnosed in 26 pts ( I group), ischaemic cardiomyopathy - in 27 pts ( II group). Geometry and function of left and right ventricles, grade of mitral regurgitation (MR), pulmonary artery systolic pressure were investigated according to the recommendations of American Society of Echocardiography (2005). Right ventricular systolic function was assessed using tricuspid valve annular motion (TAPSE) with M-mode cursor oriented to the junction of the tricuspid valve plane with the RV free wall. LV end diastolic diameter index (LVEDDi), LV EF, the severity of mitral regurgitation, RV end diastolic diameter (RVEDD) and systolic pulmonary artery pressure (PAP sist) didn't differ between the groups (Tab.). The pts of group I had more severe tricuspidal regurgitation (2,67±0,12 vs. 1,93±0,13; p<0,05) and worse tricuspid valve annular motion (TAPSE) (12,83±0,49 vs. 15,96±0,57; p<0,001). NYHA functional class was worse in the pts with non ischaemic dilated cardiomyopathy. III-IV NYHA functional class was revealed in 100% of group I vs. 80% of group II pts. (p<0,05). Conclusion: More pronounced RV systolic dysfunction was determined in pts with non ischaemic dilated cardiomyopathy despite the similar LV dysfunction and MR severity of the pts with ischaemic cardiomyopathy. Depressed RV systolic function corelates with worse clinical status, NYHA functional class in the patients with low LV EF.