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The diagnostic value of Chlamydia trachomatis antibody testing in the diagnosis of tubal pathology among infertile patients / E. Tvarijonavičienė, K. Persson, R. Nadišauskienė, L. Vaidotienė, H. Stankevičius, R. Mačiulevičienė
Type of publication
Tezės Web of Science duomenų bazėje / Theses in Web of Science database (T1a1)
Author(s)
Persson, K. | Department of Clinical Microbiology, University Hospital in Malmo, Sweden |
Title
The diagnostic value of Chlamydia trachomatis antibody testing in the diagnosis of tubal pathology among infertile patients / E. Tvarijonavičienė, K. Persson, R. Nadišauskienė, L. Vaidotienė, H. Stankevičius, R. Mačiulevičienė
Publisher (trusted)
Elsevier |
Is Referenced by
Date Issued
Date Issued |
---|
2009-10-04 |
Extent
p. S642-S643, no. P810.
Is part of
International journal of gynecology and obstetrics : Abstracts of XIX FIGO World Congress of Gynecology and Obstetrics : 4th-9th October 2009, Cape Town, South Africa / International Federation of Gynecology and Obstetrics. Limerick : Elsevier, 2009, vol. 107, suppl. 2, October.
Version
Originalus / Original
Description
Yra ir CD.
Field of Science
Abstract
Objective: To evaluate the diagnostic value of Chlamydia trachomatis IgG antibody testing (CAT) in the diagnosis of tubal pathology among infertile patients. Materials and Methods: A prospective cross-sectional study at Kaunas University of Medicine Hospital within the period of 18 months was performed. Consecutive infertile women formed the study group according to defined criteria. Serum samples for CAT were collected from each patient before diagnostic laparoscopy and dye test for assessment of tubal pathology. CAT were tested using a micro-immunofluorescence assay (MIF). Sensitivity, specificity, likelihood ratios (LR) and post-test probabilities for predicting tubal pathology as determined by laparoscopy and dye test were calculated for different cut-off levels of CAT. Results: The study population comprised 149 infertile women. For 67 (45%) patients positive CAT result (>16) was found, 82 (55%) patients were negative for CAT (<16). Increasing the cutoff threshold improves specificity (from 75.6% to 97.8%) and LR+ (from 3.1 to 6.9) at the expense of sensitivity (from 76.3% to 15.3%) and LR− (from −0.3 to −0.9). Changes in post-test probabilities were observed as well. Conclusions: The diagnostic performance of CAT in the diagnosis of tubal pathology is fair. The diagnostic accuracy of CAT depends on the cut-off level. The optimum cut-off threshold of CAT should be considered according the aim of screening.
Type of document
type::text::conference output::conference proceedings::conference paper
ISSN (of the container)
0020-7292
Other Identifier(s)
(LSMU ALMA)990000745460107106
Coverage Spatial
Pietų Afrikos Respublika / South Africa (ZA)
Language
Anglų / English (en)
Journal | IF | AIF | AIF (min) | AIF (max) | Cat | AV | Year | Quartile |
---|---|---|---|---|---|---|---|---|
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS | 1.408 | 2.188 | 2.188 | 2.188 | 1 | 0.644 | 2009 | Q3 |
Journal | IF | AIF | AIF (min) | AIF (max) | Cat | AV | Year | Quartile |
---|---|---|---|---|---|---|---|---|
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS | 1.408 | 2.188 | 2.188 | 2.188 | 1 | 0.644 | 2009 | Q3 |