Use this url to cite publication: https://hdl.handle.net/20.500.12512/68750
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Heterogeneity of breast cancer: the importance of interaction between different tumor cell populations : review article / Indrė Januškevičienė, Vilma Petrikaitė
Type of publication
Straipsnis Web of Science duomenų bazėje / Article in Web of Science database (S1a)
Author(s)
Vilniaus universitetas. Biotechnologijos institutas |
Title
Heterogeneity of breast cancer: the importance of interaction between different tumor cell populations : review article / Indrė Januškevičienė, Vilma Petrikaitė
Publisher (trusted)
Pergamon-Elsevier |
Is Referenced by
Date Issued
Date Issued |
---|
2019-10-24 |
Extent
p. 1-10.
Is part of
Life sciences. Oxford : Pergamon-Elsevier Science Ltd, 2019, vol. 239.
Version
Originalus / Original
Field of Science
Abstract
Breast cancer is the most common cancer and the second leading cause of cancer-related death in women worldwide. Despite the early detection of breast cancer and increasing knowledge of its biology and chemo-resistance, metastatic breast cancer is largely incurable disease. We provide a review of the intertumor and intratumor heterogeneity, explain the differences between triple-negative breast cancer subtypes. Also, we describe the interaction of breast tumor cells with their microenvironment cells and explain how this interaction contributes to the tumor progression, metastasis formation and resistance to the treatment.Conclusion Understanding the molecular and cellular mechanisms of tumor heterogeneity that are relevant to the development of treatment resistance is a major area of research. Identification of differences between populations and their response to anticancer drugs would help to predict the potential resistance to chemotherapy and thus would help to select the most suitable anticancer treatment.
Type of document
type::text::journal::journal article
ISSN (of the container)
0024-3205
1879-0631
WOS
000501363000047
Other Identifier(s)
(LSMU ALMA)990000996460107106
Coverage Spatial
Jungtinė Karalystė / United Kingdom of Great Britain and Northern Ireland (GB)
Language
Anglų / English (en)
Bibliographic Details
109