EI Cukrinio diabeto laboratorija (09.03)

Author: Anat Zilberg Scientific Supervisor: Dr. Rytas Ostrauskas Research Title: Screening of Similarities and Differences in Detection and Treatment Among Patients with Type 2 Diabetes in Lithuania and Israel Aim: The review will likely begin with an introduction to the prevalence of Type 2 diabetes in both countries and the importance of early detection and effective treatment to manage the condition and prevent complications. The review may also touch on the economic and social impact of Type 2 diabetes on the healthcare system and society as a whole. Next, the review will delve into the specifics of how Type 2 diabetes is detected and diagnosed in Lithuania and Israel, including the screening tests used and any differences in the criteria for diagnosis. The review may also explore the availability and accessibility of screening tests and medical resources in both countries and any challenges or barriers that may exist in detecting and diagnosing Type 2 diabetes. The review will then move on to the treatment options available for Type 2 diabetes in Lithuania and Israel, including any differences in the medications, dietary interventions, and lifestyle modifications recommended. The review may also touch on the availability and affordability of these treatments and any challenges or barriers that patients may face in accessing them. Finally, the review concludes with a summary of the similarities and differences identified in the detection and treatment of Type 2 diabetes among patients in Lithuania and Israel, as well as any potential implications for improving care and outcomes in both countries. Objectives:

1. To evaluate the situation of type 2 diabetes in Lithuania.
2. To evaluate the situation of type 2 diabetes in Israel.
3. To evaluate the similarities and differences of the type 2 diabetes situation in Lithuania and Israel. 4 Methods: The search engine used for data collection and clinical studies was the online database "PubMed". The keywords used for searching the articles for the systematic review were: Diabetes, Type 2 diabetes, prevalence, classification, diagnosis, treatment, Ethnic groups, Medications, Prevention, Early Detection, Public health, Lithuania, and Israel. A total of 72,898 articles were identified from the initial search, After filtering [according to types of studies, time of publication] and manual screening, 42 articles were selected for analysis. Results: Lithuania and Israel have significant rates of diabetes prevalence, with Lithuania having a prevalence of 9.5% and Israel having a prevalence of 9.9%. Israel has a higher diabetes prevalence percentage in all categories compared, to age, gender, diabetes-related deaths, and diabetes-related health expenditure per person. Lithuania and Israel have different methods for diabetes detection and access to healthcare professionals and diabetes management supplies. Both countries emphasize lifestyle interventions and medication treatment options. both have established diabetes programs to improve management Conclusions: The high prevalence rates of diabetes highlight the need for effective prevention and management strategies. Lithuania and Israel have different methods for diabetes detection and advanced technology for diabetes management. Access to healthcare professionals and diabetes management supplies is limited in Lithuania, but this is not specified for Israel. Both countries emphasize lifestyle interventions and metformin as first-line treatment options for diabetes. Second-line therapy options differ based on HbA1c levels in Lithuania and BMI in Israel. Diabetes detection and treatment coverage are available free of charge for both countries, which helps citizens maintain their diabetes care.

[...]. Darbo tikslas. Įvertinti kūno sudėtį, angliavandenių ir riebalų apykaitą, gyvenseną bei genetinę cukrinio diabeto predispoziciją moterims, kurioms prieš 15 metų ar daugiau nustatytas gestacinis diabetas, ir jų vaikams. Uždaviniai: 1. Įvertinti nėščiųjų moterų antsvorio/nutukimo paplitimą 30 metų laikotarpyje. 2. Įvertinti kūno sudėtį moterims, kurioms anamnezėje diagnozuotas gestacinis diabetas. 3. Įvertinti angliavandenių ir riebalų apykaitą, atsparumą insulinui, inkretinų koncentraciją moterims, kurioms anamnezėje diagnozuotas gestacinis diabetas. 4. Įvertinti moterų, kurioms anamnezėje diagnozuotas gestacinis diabetas, gyvenseną: mitybą ir fizinį aktyvumą. 5. Įvertinti 2 tipo cukrinį diabetą predisponuojančio TCF7L2 geno VNP (rs7901695, rs7903146, rs7895340, rs11196205, rs12255372) alelių paplitimus moterims, kurioms anamnezėje nustatytas gestacinis diabetas, ir palyginti su bendrosios populiacijos moterų TCF7L2 geno VNP paplitimais. 6. Palyginti tos pačios mamos vaikų, gimusių esant gestaciniam diabetui ir normaliam nėštumui, sveikatos būklę: antropometrinius parametrus, angliavandenių/riebalų apykaitą ir genetinę predispoziciją sirgti 2 tipo cukriniu diabetu. [...].