Lašaitė, Lina

Introduction: Eating disorders (ED) and disordered eating behaviors are common in youth with type 1 diabetes (T1D) and may impact metabolic control and quality of life. Objectives: To evaluate differences in ED symptoms based on subjective health perception in adolescents and young adults with T1D. Methods: A cross-sectional study included 57 individuals aged 14–25 years with T1D. Participants were divided into two groups based on self-rated health (good vs poor). ED symptoms were assessed using the Eating Disorder Examination Questionnaire (EDE-Q 6.0), which evaluates behavioral frequency and attitudinal subscales over the past 28 days, a higher score reflects either greater severity or frequency. Group comparisons were performed using appropriate statistical tests. Results: Participants with poor self-rated health had significantly higher ED psychopathology. Eating concern (0.5±0.72 vs.1±2.1, p<0.001), shape concern (1.1±1.2 vs 2.8±1.5, p<0.001), weight concern (1.1±1.2 vs 2.6±1.7, p<0.001), and total EDE-Q score (1.1±1.1 vs 2.4±1.5, p<0.001) were all significantly higher. They also reported more binge eating episodes (3.9±6.6 vs 6.5±6.4, p=0.013), episodes with loss of eating control (1.1±3.5 vs 6.3±8.7, p<0.001), and more binge eating days (0.7±0.9 vs 5.4±7.0, p<0.001). Importantly, no significant differences were observed between groups in objective disease-related parameters, including diabetes duration, age at diagnosis, BMI, HbA1c, and time in range. Conclusions: Poor subjective health perception in youth with T1D is strongly associated with increased ED symptomatology, independent of metabolic parameters. Screening for ED should include patient-reported health perception as a potential risk indicator.

Introduction: Disordered eating behaviors in T1D may influence metabolic outcomes, yet their relationships with clinical parameters remain insufficiently characterized. Objectives: To analyze correlations between eating disorders (ED) symptoms and metabolic as well as clinical parameters in youth with T1D. Methods: A cross-sectional analysis of 57 individuals aged 14–25 years with T1D was performed. ED symptoms were assessed using the EDE-Q 6.0 questionnaire. Correlations between EDE-Q scores and BMI, HbA1c, time in range, insulin dose, disease duration, and age at diagnosis were analyzed using correlation coefficients. Results: Higher BMI was significantly associated with increased ED psychopathology, including restraint (r=0.382, p=0.004), eating concern (r=0.314, p=0.018), shape concern (r=0.354, p=0.007), weight concern (r=0.364, p=0.006), total score (r=0.383, p=0.004), binge eating with loss of control (r=0.326, p=0.017), and binge eating days (r=0.389, p=0.004). Compulsive exercise also correlated with BMI (r=0.351, p=0.009). Higher HbA1c was negatively associated with compulsive exercise (r=- 0.363, p=0.032). Time in range was negatively correlated with shape concern (r=-0.350, p=0.029), weight concern (r=-0.327, p=0.042), and binge eating frequency (r=-0.372, p=0.021). Conclusions: ED symptoms in youth with T1D are significantly associated with BMI and glycemic metrics. Higher ED severity correlates with higher BMI and poorer glycemic profiles, highlighting the importance of integrated metabolic and psychological assessment.

TEMOS AKTUALUMAS Medicinos studentai patiria didelį akademinį krūvį ir stresą, kuris dažnai yra siejamas su prastesne miego kokybe. Nors psichologinis stresas ir miego kokybė gana plačiai ištirti, šie aspektai mažai nagrinėti jaunų sveikų žmonių populiacijose. Trūksta duomenų, kurie leistų palyginti skirtingų medicinos studijų kursų studentus ir atskleisti streso ir miego kokybės tarpusavio sąsajas. DARBO TIKSLAS (-AI) Įvertinti miego kokybės skirtumus, susijusius su patiriamu psichologiniu stresu, tarp 1-ojo ir 5-ojo kurso medicinos studentų. [...].

TEMOS AKTUALUMAS 1 tipo cukrinis diabetas (1TCD) yra lėtinė liga, reikalaujanti nuolatinės glikemijos kontrolės ir intensyvios savikontrolės, kuri ypač paauglystėje ir jauname amžiuje gali būti susijusi su reikšmingais psichologiniais iššūkiais. Pastaraisiais metais vis dažniau atkreipiamas dėmesys į valgymo sutrikimų, ypač diabulimijos, paplitimą šioje pacientų grupėje. DARBO TIKSLAS (-AI) Įvertinti skirtingų lyčių ir skirtingo kūno masės indekso pacientų, sergančių 1TCD, su 1TCD susijusią gyvenimo kokybę ir valgymo sutrikimų požymių lygį. [...].

Aim To investigate quality of life (QoL) in patients with type 2 diabetes (T2DM) experiencing low perceived psychological stress level and high perceived psychological stress level. Methods Perceived psychological stress level and QoL were assessed in 146 patients with T2DM (57 men, 89 women, age 56.7G12.6 years, T2DM duration 7.4G6.9 years, body mass index (BMI) 33.6G5.7 kg/m2 , HbA1c level 7.7G1.6%), using Perceived Stress Scale (a higher score denotes a higher level of stress) and WHO Bref Quality of Life questionnaire (a higher score denotes better QoL). Results. Patients with high perceived stress level had lower scores in physical health (10.9G 1.6 vs. 13.9G2.4, P!0.001), psychological health (11.4G2.8 vs. 13.7G2.1, P Z 0.018), and social relations domains (12.3G1.9 vs. 13.6G2.6, P Z 0.038) than those with low perceived stress level. No significant differences were found in QoL environmental domain as well as in age, T2DM duration, BMI, HbA1c level between patients experiencing low and high perceived stress. Perceived stress level in patients with T2DM correlated negatively with QoL physical health score (rZ -0.255, P Z 0.015). In conclusion. Patients with type 2 diabetes experiencing high perceived psychological stress level have worse quality of life in terms of physical health, psychological health and social relations than those with low level of perceived psychological stress.Perceived stress level in patients with type 2 diabetes is related to physical health.

The aim: to assess quality of life (QoL) and profile of mood states in patients with childhood-onset hypopituitarism and growth hormone (GH) deficiency during the discontinuation of recombinant growth hormone (rGH) replacement therapy at the transition from adolescence to adulthood. Methods: mood states and QoL were assessed in 136 (85 men, 51 women, age 16.8±1.1 years) patients during discontinuation of rGH replacement and 82 (40 men, 42 women, age 16.5±1.7 years) control individuals using the Profile of Mood States2 (POMS2) and the Quality of Life - Assessment of Growth Hormone Deficiency in Adults (QoL-AGHDA) questionnaires. Results: No difference in QoL was between patients and controls, but patients had higher levels of tension-anxiety (median 9.0 score vs. 6.0 score, p< 0.001), depression-dejection (median 9.0 score vs. 8.0 score, p=0.042), fatigue-inertia (median 9.0 score vs. 6.0 score, p< 0.001), confusion-bewilderment (median 4.0 score vs. 3.0 score, p=0.003) than controls. Basal cortisol concentration correlated negatively with QoL-AGHDA score (r= -0.288, p=0.012), depression-dejection score (r= -0.317, p=0.005). Height correlated negatively with anger-hostility (r= -0.223, p=0.010), fatigue-inertia (r= -0.188, p=0.030) scores. Body mass index (BMI) correlated positively with fatigue-inertia score (r= 0.181, p=0.040). Age at the discontinuation of rGH replacement correlated negatively with QoL AGHDA score (r= -0.204, p=0.026), depression-dejection (r= -0.460, p=0.021), anger hostility (r= -0.190, p=0.040), fatigue-inertia (r= -0.205, p=0.026) scores. Conclusion: mood states (higher tension-anxiety, depression-dejection, fatigue-inertia, confusion-bewilderment), but not disease-specific QoL are impaired in patients with childhood-onset growth hormone deficiency during the discontinuation of rGH replacement therapy at the transition from adolescence to adulthood.

Temos aktualumas. 2 tipo cukriniu diabetu (2TCD) sergančių pacientų miego kokybė yra svarbi bendrai jų savijautai ir gyvenimo kokybei [1]. Prasta miego kokybė, ypač nepakankama miego trukmė ar sutrikęs miego režimas, gali padidinti rezistentiškumą insulinui ir taip pabloginti glikemijos kontrolę, sukelti nuovargį ir prastą emocinę būklę [2]. [...] .

Aim to assess sleep quality in patients with type 2 diabetes (T2D) experiencing low perceived psychological stress and high perceived psychological stress. Methods Perceived stress level and sleep quality were assessed in 154 patients with T2D (58 men, 96 women, age 58.7G11.8 years), using Perceived Stress Scale (a higher score denotes a higher level of perceived stress) and Pittsburgh Sleep Quality Index (a higher score denotes worse sleep quality). Results Patients with T2D with high stress level had worse subjective sleep quality (PZ0.027), higher use of sleeping medication (PZ0.023), daytime dysfunction (P!0.001) than those with low stress level. No significant differences were found in sleep latency, sleep duration, habitual sleep efficiency and sleep disturbances as well as in T2D duration, body mass index and glycated haemoglobin (HbA1c) level between patients experiencing low and high perceived stress. Perceived stress level in patients with T2D correlated with subjective sleep quality (rZ 0.260, PZ0.002), sleep duration (rZ0.228, PZ0.005), use of sleep medication (rZ0.245, PZ0.004), daytime dysfunction (rZ0.326, P!0.001). In conclusion, patients with type 2 diabetes experiencing high perceived psychological stress level have worse subjective sleep quality, higher use of sleeping medication, daytime dysfunction than patients experiencing low perceived stress level. Perceived stress level in patients with type 2 diabetes is related to subjective sleep quality, sleep duration, use of sleep medication, daytime dysfunction

To assess sleep quality in relation to perceived stress in patients with type 2 diabetes (T2DM) and age- and sex-matched controls.

Tikslas. Įvertinti hipopituitarizmu sergančių paauglių gyvenimo kokybę po pakeičiamojo gydymo augimo hormonu. [...].