Laboratories

Head of the Laboratory
Prof. Dr. Gediminas Jaruševičius
Phone: +370 37 326 094
Email: gediminas.jarusevicius@lsmu.lt

Laboratory contacts

Main fields of activity:

• Development of cardiology systems for diagnostics, rehabilitation and sports medicine (collaboration with the Lithuanian Sports University, LSMU Faculty of Public Health and LSMU Sports Institute).
• Assessment of human functional state using the methods of non-linear analysis and complex systems theory (in cooperation with KTU researchers and international partners).
• “Assessment of the dynamics of cardiovascular system complexity during cardiac interventional procedures (coronary angiography, angioplasty, and bypass surgery)” (collaboration with the KTU researchers and international partners).
• Development of diagnostic and prognostic algorithms and their application during coronary angioplasty and bypass procedures for evaluation of the success of the procedure and prediction of the long-term prognosis of patient survival and quality of life (collaboration with the researchers of the Department of Physiology of LSMU).

Head of the Laboratory
Prof. Dr. Eglė Ereminienė
Phone: +370 37 326 149
Email: egle.ereminiene@lsmu.lt

Laboratory contacts

Main fields of activity:

• Assessment of prognostic factors of the perioperative period determining respective treatment outcomes in patients with cardiovascular diseases.
• Determination of treatment tactics in patients with multiple coronary artery lesions after primary percutaneous coronary intervention: implications for remote outcomes.
• Evaluation of the value of myocardial deformability indicators in the detection of myocardial fibrosis in the presence of heart valve malformations.
• Associations between depression correction and changes in heart rate variability parameters (state at rest and response to psychological/arithmetic stress test) in patients after cardiac surgery.
• Experimental study of the effect of ultrasonic (cavitation) energies on the function of isolated blood vessels using waveguides of different configurations and power.

Head of the Laboratory
Prof. Dr. Vytenis Arvydas Skeberdis
Phone: +370 37 302 880
Email: arvydas.skeberdis@lsmu.lt

Laboratory contacts

Main fields of activity:

• Investigation of the influence of B3-adrenergic receptors and their polymorphisms on the L-type calcium current and contractile force of the human heart (collaboration with the Laboratory of Cellular and Molecular Cardiology, Faculty of Pharmacy, University of Paris XI (Dr Rodolphe Fischmeister).
• Investigation of the molecular and genetic mechanisms of short QT syndrome, which can lead to syncope, ventricular tachycardias and sudden death (collaboration with Aarhus University, Denmark).
• The mechanisms regulating midbody inheritance and its role in cancer cell proliferation and invasiveness (collaboration with the Department of Cell and Developmental Biology, University of Colorado, USA).
• Stem and cancer cell viability and other properties under stress conditions by chromatography, fluorescence microscopy and electrophysiology (collaboration with the Environmental Research Centre of Vytautas Magnus University and the Institute of Experimental and Clinical Pharmacology of Kiel University (Germany).

Head of the Laboratory
Habil. Dr. Jonas Jurevičius
Phone: +370 37 302 877
Email: jonas.jurevicius@lsmu.lt

Laboratory contacts

Main fields of activity:

• Investigation of hormonal, metabolic and cell volume-dependent mechanisms of myocardial regulation of ionic currents and compartmentation of signalling systems in cardiac cells.
• Investigation of the mechanisms of heart failure, cardiac arrhythmia genesis, hypoxia, ischaemia, reperfusion, antiarrhythmic, and other pharmacological agents in the myocardium.
• Investigation of the detection and regulatory mechanisms of cardiac myocyte ion channels, including magnesium-sensitive TRPM6 and TRPM7 channels.
• Application of optical techniques to the study of cardiac excitation, arrhythmias, and their mechanisms of occurrence.
• Pharmacodynamic and pharmacokinetic studies on Elsholtzia ciliata (Vietnamese balm).

Head of the Laboratory
Prof. Habil. Dr. Vaiva Lesauskaitė
Phone: +370 37 302 874
Email: vaiva.lesauskaite@lsmu.lt

Laboratory contacts

Main fields of activity:

• Genetic epidemiology of cardiovascular diseases (CVDs) (collaboration with the LSMU Cardiology Clinics and Clinics of Cardiac, Thoracic and Vascular Surgery).
• Investigation of candidate genes and variants relevant to the morphogenesis of cardiovascular diseases.
• Pharmacogenomic studies of cardiovascular diseases (collaboration with the LSMU Cardiology Clinics and Clinics of Cardiac, Thoracic and Vascular Surgery).

Head of the Laboratory
Prof. Dr. Dalia Lukšienė
Phone: +370 37 302 892
Email: dalia.luksiene@lsmu.lt

Laboratory contacts

Main fields of activity:

• Implementation of population-based registries for ischaemic heart disease (acute myocardial infarction) and stroke(collaboration with the Kaunas Clinics of the LSMU Kaunas Hospital, LSMU Kaunas Hospital, Kaunas City Ambulance Station, Kaunas City Polyclinic, Institute of Hygiene).
• Epidemiological studies on cardiovascular and other chronic diseases and their risk factors in the adult population (collaboration with the LSMU Faculty of Public Health).
• Epidemiological studies on cardiovascular diseases and their risk factors in children and adolescent population (collaboration with Kaunas district municipality, Public Health Burau of Kaunas district municipality).

Head of the Laboratory
Prof. Dr. Edgaras Stankevičius
Phone: +370 37 327 257
Email: edgaras.stankevicius@lsmu.lt

Laboratory contacts

Main fields of activity:

• Investigation of cardiovascular functions.
• Research on medicinal products and drug application models in collaboration with all clinical departments.

Head of the Laboratory
Prof. Dr. Vilma Petrikaitė
Phone: +370 37 327 316
Email: vilma.petrikaite@lsmu.lt

Laboratory contacts

Main fields of activity:

• Investigation of biological effects of substances (antioxidant, antimicrobial, anticancer, antimetastatic, anti-inflammatory, and other activities).
• Material permeability studies in 2D and 3D cell cultures.
• Development of functionalized nanoformulations for targeted therapies.
• Assessment of the effects of hypoxia and pH on cell growth, migration, and invasion.
• Assessment of interactions between cell populations.

Head of the Laboratory
Dr. Lina Kraujalienė
Phone: +370 37 302 880
Email: lina.kraujaliene@lsmu.lt

Laboratory contacts

Main fields of activity:

• Structural-functional studies and biophysical properties of connexin-based gap junctions.
• Modelling and experimental studies of cardiac and neural cell networks.
• The effect of connexins on the genesis and course of cardiovascular diseases

Implemented projects:

„Study of connexin 26 mutations in syndromic deafness“